Association of Superior Vena Cava Syndrome with Sleep Apnea Investigation Using an Impulse Oscillometry System英文文献资料.docVIP

International Journal of Clinical Medicine, 2012, 3, 270-275 /10.4236/ijcm.2012.34053 Published Online July 2012 (http://www.SciRP.org/journal/ijcm) Association of Superior Vena Cava Syndrome with Sleep Apnea: Investigation Using an Impulse Oscillometry System Masanori Yokoba , Naohito Ishii , Tsuyoshi Ichikawa , Mayuko Wada , Hisashi Mitsufuji , 1,2* 1 3 2 2 2 1,2 Masaru Kubota 2 , Noriyuki Masuda , Masato Katagiri 1 School of Allied Health Sciences, Kitasato University, Kanagawa, Japan; 2 Division of Respiratory Medicine, Kitasato University Hospital, Kanagawa, Japan; * Email: myoko@kitasato-u.ac.jp 3 Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan. Received March 16 , 2012; revised April 28 , 2012; accepted May 15 , 2012 th th th ABSTRACT Superior vena cava syndrome (SVCS) patients sometimes show signs of obstructive sleep apnea (OSA). However, the mechanism causing hypoxia during sleep in SVCS patients is still uncertain. The aim of this study was to elucidate 1) the changes in central and peripheral respiratory resistance with SVCS; and 2) interpret the mechanism underlying the development of hypoxia during sleep in patients with SVCS related to OSA. Ten SVCS patients related to a neoplasm were recruited for this study. The degree of apnea hypopnea index (AHI) for OSA was evaluated by portable diagnosing device before and after SVCS treatment. We also analyzed the airway resistance and reactance quantitatively in the su- pine position by Master Screen impulse oscillometry system (MS-IOS ). After SVCS treatment, mean values of AHI ? were significantly decreased fro