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Boesenbergia rotunda From Ethnomedicine to Drug Discovery英文文献资料
HindawiPublishingCorporation
Evidence-BasedComplementaryandAlternativeMedicine
Volume2012,ArticleID473637,25pages
doi:10.1155/2012/473637
ReviewArticle
Boesenbergiarotunda:FromEthnomedicinetoDrugDiscovery
TanEng-Chong,1,2LeeYean-Kee,2,3CheeChin-Fei,2,3,4HehChoon-Han,2,3,5
WongSher-Ming,6,7ChristinaThioLi-Ping,1,2,6FooGen-Teck, 2,7
NorzulaaniKhalid,6,7NoorsaadahAbdRahman,2,3SaifulAnuarKarsani, 2,6
ShatrahOthman,1,2RozanaOthman,2,5andRohanaYusof 1,2
1
2
3
4
DepartmentofMolecularMedicine,FacultyofMedicine,UniversityofMalaya,50603KualaLumpur,Malaysia
DrugDesignandDevelopmentResearchGroup(DDDRG),UniversityofMalaya,50603KualaLumpur,Malaysia
DepartmentofChemistry,FacultyofScience,UniversityofMalaya,50603KualaLumpur,Malaysia
DivisionofPharmacy,SchoolofPharmacyandHealthSciences,InternationalMedicalUniversity(IMU),BukitJalil,
57000KualaLumpur,Malaysia
5
6
7
DepartmentofPharmacy,FacultyofMedicine,UniversityofMalaya,50603KualaLumpur,Malaysia
InstituteofBiologicalSciences,FacultyofScience,UniversityofMalaya,50603KualaLumpur,Malaysia
BiotechnologyandBioproductResearchCluster(UMBIO),UniversityofMalaya,50603KualaLumpur,Malaysia
CorrespondenceshouldbeaddressedtoTanEng-Chong,tanengchong123@
Received26June2012;Accepted6August2012
AcademicEditor:Y.Ohta
Copyright?2012TanEng-Chongetal. This is an open access article distributed under the Creative Commons Attribution
License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly
cited.
BoesenbergiarotundaisaherbfromtheBoesenbergiageneraundertheZingiberaceaefamily.B.rotundaiswidelyfoundinAsian
countrieswhereitiscommonlyusedasafoodingredientandinethnomedicinalpreparations.Thepopularityofitsethnomedicinal
usagehasdrawntheattentionofscientistsworldwidetofurtherinvestigateitsmedicinalproperties.Advancementindrugdesign
anddiscoveryresearchhasledtothedevelopmentofsyntheticdrugsfromB.rotundametabolitesviabioinformaticsandmedicinal
chemistrystudies.Furthermore,withtheadventofgenomics,transcriptomi
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