Breast Cancer Preoperative Staging Does Contrast-Enhanced Magnetic Resonance Mammography Modify Surgery英文文献资料.docVIP

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Breast Cancer Preoperative Staging Does Contrast-Enhanced Magnetic Resonance Mammography Modify Surgery英文文献资料.doc

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Breast Cancer Preoperative Staging Does Contrast-Enhanced Magnetic Resonance Mammography Modify Surgery英文文献资料

SAGE-HindawiAccesstoResearch InternationalJournalofBreastCancer Volume2011,ArticleID757234,10pages doi:10.4061/2011/757234 ClinicalStudy BreastCancerPreoperativeStaging:DoesContrast-Enhanced MagneticResonanceMammographyModifySurgery? ChiaraPeronoBiacchiardi, DavideBrizzi, FrancoGenta, EugenioZanon, 1 2 1 2 MarcoCamanni, andFrancescoDeltetto 1 1 1 Ginteam,Mini-InvasiveGynaecologicalandBreastSurgeryUnit,EvangelicalHospital,ASLTO1,ViaSilvioPellico19, 10125Torino,Italy 2 BreastRadiologyUnit,EvangelicalHospital,ASLTO1,ViaSilvioPellico19,10125Torino,Italy CorrespondenceshouldbeaddressedtoChiaraPeronoBiacchiardi,chiara.peronobiacchiardi@to.omceo.it Received31December2010;Accepted31March2011 AcademicEditor:WilliamDooley Copyright?2011ChiaraPeronoBiacchiardietal. This is an open access article distributed under the Creative Commons AttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkis properlycited. Womenwithnewlydiagnosedbreastcancermayhavelesionsundetectedbyconventionalimaging.Recentlycontrast-enhanced magneticresonancemammography(CE-MRM)showedhighersensitivityinbreastlesionsdetection.Thepresentanalysiswas aimedatevaluatingthebene?tofpreoperativeCE-MRMinthesurgicalplanning.From2005to2009,525consecutivewomen (25–75years)withbreastcancer,newlydiagnosedbymammography,ultrasound,andneedle-biopsy,underwentCE-MRM.The medianinvasivetumoursizewas19mm.In144patients,CE-MRMidenti?edadditionallesions.Aftersecondlook,119patients underwentadditionalbiopsy.CE-MRMalteredsurgeryin118patients:57receiveddoublelumpectomyorwiderexcision(41ben- e?cial),41requiredmastectomy(40bene?cial),and20underwentcontralateralsurgery(18bene?cial).Theoverallfalse-positive ratewas27.1%(39/144).CE-MRMcontributedsigni?cantlytothemanagementofbreastcancer,suggestingmoreextensivedisease in144/525(27.4%)patientsandchangingthesurgicalplanin118/525(22.5%)patients(99/525,18.8%bene?cial). 1.Introduction MRM) has