Breast Conserving Surgery and Sentinel Lymph Node Biopsy under Local Anesthesia for Breast Cancer英文文献资料.docVIP

Journal of Cancer Therapy, 2012, 3, 810-813 /10.4236/jct.2012.325102 Published Online October 2012 (http://www.SciRP.org/journal/jct) Breast Conserving Surgery and Sentinel Lymph Node Biopsy under Local Anesthesia for Breast Cancer Shinichiro Kashiwagi , Naoyoshi Onoda, Tsutomu Takashima, Yuka Asano, Naoki Aomatsu, * Masanori Nakamura, Hidemi Kawajiri, Tetsuro Ishikawa, Kosei Hirakawa Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka, Japan. * Email: spqv9ke9@view.ocn.ne.jp Received August 21 , 2012; revised September 23 , 2012; accepted October 8 , 2012 st rd th ABSTRACT Background: Breast conserving surgery and sentinel lymph node biopsy has become the standard operation for early breast cancer. This operation has been performed under local anesthesia for patients that would like short-term admis- sion or for those not indicated for general anesthesia due to complications. This report presents the outcomes of breast conserving surgery and sentinel lymph node biopsy under local anesthesia. Patients and Methods: The study included 61 patients with breast cancer that were all definitely diagnosed before surgery. The indications were preoperatively diagnosed localized DCIS, invasive carcinoma measuring less than 3 cm in tumor diameter on ultrasound, and tumors with negative axillary lymph nodes. The surgical procedures included breast conserving surgery associated with sentinel lymph node navigation biopsy. Results: The surgery could be performed under local anesthesia in all 61 patients, and no patient was converted to general anesthesia. Four patients had sentinel lymph node metastasis. Surgical stumps were positive in 18 patients (29.5%). Ten Gy of boost irradiation of the tumor bed was added to the conventional breast irra- diation for these patients. Th