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Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children英文文献资料
HindawiPublishingCorporation
InternationalJournalofPediatrics
Volume2012,ArticleID270515,6pages
doi:10.1155/2012/270515
ClinicalStudy
CardiorespiratoryFitness,MetabolicRisk,
andIn?ammationinChildren
AntoniosD.Christodoulos,HelenT.Douda,
andSavvasP.Tokmakidis
DepartmentofPhysicalEducationandSportScience(T.E.F.A.A.),DemocritusUniversityofThrace,
69100Komotini,Greece
CorrespondenceshouldbeaddressedtoSavvasP.Tokmakidis,stokmaki@phyed.duth.gr
Received2July2011;Revised6October2011;Accepted20October2011
AcademicEditor:EmmanuelKatsanis
Copyright?2012AntoniosD.Christodoulosetal. This is an open access article distributed under the Creative Commons
AttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkis
properlycited.
Theaimofthisstudywastoinvestigatetheindependentassociationsamongcardiorespiratory?tness,metabolicsyndrome(MetS),
andC-reactiveprotein(CRP)inchildren.Thesampleconsistedof112children(11.4 ± 0.4years).Datawasobtainedforchildren’s
anthropometry,cardiorespiratory?tness,MetScomponents,andCRPlevels.MetSwasde?nedusingcriteriaanalogoustothe
AdultTreatmentPanelIIIde?nition.AMetSriskscorewasalsocomputed.PrevalenceoftheMetSwas5.4%,withoutgender
di?erences. Subjects with low ?tness showed signi?cantly higher MetS risk (P 0.001) and CRP (P 0.007), compared to
thehigh-?tnesspupils.However,di?erencesinMetSrisk,andCRPbetween?tnessgroupsdecreasedwhenadjustedforwaist
circumference.Thesedataindicatethatthemechanismslinkingcardiorespiratory?tness,MetSriskandin?ammationinchildren
areextensivelya?ectedbyobesity.Interventionstrategiesaimingatreducingobesityandimprovingcardiorespiratory?tnessin
childhoodmightcontributetothepreventionoftheMetSinadulthood.
1.Introduction
children are independent or partly due to the mediating
e?ect of obesity, since the existing data are limited and
equivocal[5,6].
Theprevalenceandseverityofobesityisincreasingdramat-
icallyamongchildrenandadolescentsinmanypartsofthe
world,whereasprevalence
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