Scyphiphin C, a New Iridoid from Scyphiphora hydrophyllacea 英文参考文献.docVIP

Molecules 2010, 15, 2473-2477; doi:10.3390/moleculeOPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Scyphiphin C, a New Iridoid from Scyphiphora hydrophyllacea Cui-Lian Feng 1,?, Ming-Fu Gong 2,?, Yan-Bo Zeng 1, Hao-Fu Dai 1 and Wen-Li Mei 1,* 1 Key Laboratory of Tropical Crop Biotechnology, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, Hainan, China; E-Mails: fengcuilian@126.com (C.-L.F.); zengyanbo@163.com (Y.-B.Z.); hfdai2001@ (H.-F.D.) 2 Key Laboratory of Protection Utilization of Biological Resources in Tarim Basin of Xinjiang Production Construction Corps, College of Life Science, Tarim University, Alar 843300, Xingjiang, China; E-Mail: gongmingfu98@163.com (M.-F.G.) ? These authors contributed equally to this work. * Author to whom correspondence should be addressed; E-Mail: meiwenli@. Received: 23 February 2010; in revised form: 16 March 2010 / Accepted: 1 April 2010 / Published: 8 April 2010 Abstract: Chemical investigation of the ethanol extract of the aerial parts of Scyphiphora hydrophyllacea Gaertn. collected in Hainan Province of China resulted in the isolation of a new iridoid, scyphiphin C (1) and a known iridoid glycoside, shanzhiside methyl ester (2). Their structures were elucidated by a study of their physical and spectral data. Keywords: Scyphiphora hydrophyllacea; scyphiphin C; mangrove plant; iridoid 1. Introduction Mangrove plants are groups of trees and shrubs growing along seashores in tropical and subtropical areas, which contain plenty of new and bioactive secondary metabolites due to their special eco- environment [1?3]. Scyphiphora hydrophyllacea Gaertn. F. (Rubiaceae), one of the mangrove plants, is distributed from south to southeast Asia, Caroline Islands, Australia, and New Caledonia [4]. Our previously phytochemical studies showed that flavonoids and terpenoids, espec