SDOCT Imaging to Identify Macular Pathology in Patients Diagnosed with Diabetic Maculopathy by a Digital Photographic Retinal Screening Programme 英文参考文献.docVIP

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SDOCT Imaging to Identify Macular Pathology in Patients Diagnosed with Diabetic Maculopathy by a Digital Photographic Retinal Screening Programme 英文参考文献.doc

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SDOCT Imaging to Identify Macular Pathology in Patients Diagnosed with Diabetic Maculopathy by a Digital Photographic Retinal Screening Programme 英文参考文献

SDOCTImagingtoIdentifyMacularPathologyinPatients DiagnosedwithDiabeticMaculopathybyaDigital PhotographicRetinalScreeningProgramme SarahMackenzie1*,ChristianSchmermer2,AmandaCharnley2,DawnSim1, VikasTah1 ,Martin Dumskyj2,StephenNussey2,CatherineEgan1 1MoorfieldsatStGeorge’sHospital,London,UnitedKingdom,2DepartmentofEndocrinology,StGeorge’sHospital,London,UnitedKingdom Abstract Introduction: Diabetic macular edema (DME) is an important cause of vision loss. England has a national systematic photographic retinal screening programme to identify patients with diabetic eye disease. Grading retinal photographs according to this national protocol identifies surrogate markers for DME. We audited a care pathway using a spectral- domainopticalcoherencetomography(SDOCT)clinictoidentifymacularpathologyinthissubsetofpatients. Methods: Aprospectiveauditwasperformedofpatientsreferredfromscreeningwithmildtomoderatenon-proliferative diabetic retinopathy (R1) andsurrogate markers for diabetic macular edema (M1) attending an SDOCT clinic. The SDOCT imagesweregradedbyanophthalmologistasSDOCTpositive,borderlineornegative.SDOCTpositivepatientswerereferred tothemedicalretinaclinic.SDOCTnegativeandborderlinepatientswerefurtherreviewedintheSDOCTclinicin6months. Results:Fromaregisteredscreeningpopulationof17551patientswithdiabetesmellitus,311patientsmettheinclusion criteriabetween(March2008andSeptember2009).Weanalyzedimagesfrom311patients’SDOCTclinicepisodes.There were131SDOCTnegativeand12borderlinepatientsbookedforrevisitintheOCTclinic.Twenty-fourwerereferredbackto photographic screening for a variety of reasons. A total of 144 were referred to ophthalmology with OCT evidence of definitemacularpathologyrequiringreviewbyanophthalmologist. Discussion:Thisanalysisshowsthatpatientswithdiabetes,mildtomoderatenon-proliferativediabeticretinopathy(R1)and evidenceofdiabeticmaculopathyonnon-stereoscopicretinalphotographs(M1)havea42.1%chanceofhavingnomacular edemaonSDOCTimagingasdefinedbystandard