Social, Clinical and Microbiological Differential Characteristics of Tuberculosis among Immigrants in Spain 英文参考文献.docVIP

Social,ClinicalandMicrobiologicalDifferential CharacteristicsofTuberculosisamongImmigrantsin Spain Jose′-Mar?′aGarc?′a-Garc?′a1,2*,RafaelBlanquer1,3,TeresaRodrigo1,4,JoanA.Cayla`1,5,Jose′ A. Caminero1,6,7,RafaelVidal1,8,9,Mart?′Casals1,10,11,12,JuanRuiz-Manzano1,8,13,theWorkingGroupon CompletionofTuberculosisTreatmentinSpain1 1Programa Integrado de Investigacio′n en Tuberculosis (PII TB) de la Sociedad Espan?ola de Neumolog?′a y Cirug?′a Tora′cica (SEPAR), Barcelona, Spain, 2Hospital San Agust?′n,Avile′s, Spain, 3HospitalUniversitario DrPesetdeValencia,Valencia,Spain, 4Fundacio′nRespira dela SEPAR, Barcelona,Spain,5Unidad deInvestigacio′nde TuberculosisdeBarcelona,ServiciodeEpidemiolog?′adelaAgenciadeSaludPu′blicadeBarcelona,Barcelona,Spain,6HospitalGeneralUniversitariodeGranCanariaDr Negr?′n,CanaryIslands,Spain,7InternationalUnionAgainstTuberculosisandLungDisease,Paris,France,8CIBERdeEnfermedadesRespiratorias(CIBERES),Barcelona, Spain,9HospitalVallD’Ebro′ndeBarcelona,Barcelona,Spain,10CIBERdeEpidemiolog?′aySaludPu′blica(CIBERESP),Barcelona,Spain,11DepartamentdeSalutPu′blica, Universitat de Barcelona, Barcelona, Spain, 12Departament de Ciencies Basiques, Universitat Internacional de Catalunya, Barcelona, Spain, 13Hospital Universitario GermansTr?′asyPujoldeBadalona,Badalona,Spain Abstract Background:Toidentifythedifferentialtuberculosis(TB)characteristicswithintheimmigrantpopulationwithrespectto nativesinSpain. Methodology/PrincipalFindings:AprospectivecohortstudydesignwasimplementedtoexaminetheTBcasesdiagnosed and starting standard antituberculous treatment in Spain, between January 1st 2006 and March 31st 2007. A logistic regression analysis was performed to determine differential characteristics. 1,490 patients were included in the study population,1,048nativesand442(29.7%)immigrants.Accordingtothemultivariateanalysis,thefollowingvariableswere significantlyassociatedwithimmigrantTBcases:youngerage(OR=3.79;CI:2.16–6.62),livingingroupsituation(OR=7.61;