Social-Skills and Parental Training plus Standard Treatment versus Standard Treatment for Children with ADHD – The Randomised SOSTRA Trial 英文参考文献.docVIP

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Social-Skills and Parental Training plus Standard Treatment versus Standard Treatment for Children with ADHD – The Randomised SOSTRA Trial 英文参考文献.doc

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Social-Skills and Parental Training plus Standard Treatment versus Standard Treatment for Children with ADHD – The Randomised SOSTRA Trial 英文参考文献

Social-SkillsandParentalTrainingplusStandard TreatmentversusStandardTreatmentforChildren withADHD–TheRandomisedSOSTRATrial OleJakobStoreb?1,2,3*,ChristianGluud3,PerWinkel3,ErikSimonsen2 1Child Psychiatric Clinic, Child and Adolescent Psychiatric Department, Region Zealand, Denmark, 2Psychiatric Research Unit, Region Zealand, Roskilde, Denmark, 3CopenhagenTrialUnit,CenterforClinicalInterventionResearch,Department3344,Rigshospitalet,CopenhagenUniversityHospital,Copenhagen,Denmark Abstract Objective: Toinvestigatetheeffectsofsocial-skillstrainingandparentaltrainingprogrammeforchildrenwithattention deficithyperactivitydisorder(ADHD). Methods:Weconductedarandomizedtwo-armed,parallelgroup,assessor-blindedsuperioritytrialconsistingofsocial-skills trainingplusparentaltrainingandstandardtreatmentversusstandardtreatmentalone.Asamplesizecalculationshowedat least 52 children should be included for the trial with follow up three and six months after randomization. The primary outcomemeasurewasADHDsymptomsandsecondaryoutcomesweresocialskillsandemotionalcompetences. Results56:children(39boys,17girls,meanage10.4years,SD1.31)withADHDwererandomized,28totheexperimental groupand27tothecontrolgroup.Mixed-modelanalyseswithrepeatedmeasuresshowedthatthetimecourse(y = a+bt + ct 2 ) of ADHD symptoms (p=0.40), social skills (p=0.80), and emotional competences (p=0.14) were not significantly influencedbytheintervention. Conclusions: Social skills training plus parental training did not show any significant benefit for children with attention deficithyperactivitydisorderwhencomparedwithstandardtreatment.Moreandlargerrandomizedtrialsareneeded. TrialRegistration:ClinicalTNCCitation:Storeb?OJ,GluudC,WinkelP,SimonsenE(2012)Social-SkillsandParentalTrainingplusStandardTreatmentversusStandardTreatmentforChildren withADHD–TheRandomisedSOSTRATrial.PLoSONE7(6):e37280.doi:10.1371/journal.pone.0037280 Editor:Andre′ Aleman,UniversityofGroningen,TheNetherlands ReceivedOctober17,2011;Accepte