Solitary fibrous tumor of the thigh with epithelioid features a case report 英文参考文献.docVIP

Diagnostic Pathology BioMedCentral Case Report Open Access Solitary fibrous tumor of the thigh with epithelioid features: a case report Miguel Martorell, Ana Pérez-Vallés*, Francisco Gozalbo, Jose Angel Garcia- Garcia, Jair Gutierrez and John Gaona Address: Department of Pathology, Hospital General Universitario. Valencia, Spain Email: Miguel Martorell - miguel.martorell@uv.es; Ana Pérez-Vallés* - perez_ana@gva.es; Francisco Gozalbo - gozalbo_fra@gva.es; Jose Angel Garcia-Garcia - garcia-jos@gva.es; Jair Gutierrez - jairmgh@comv.es; John Gaona - jjgaonam@ * Corresponding author Published: 18 June 2007 Received: 5 March 2007 Accepted: 18 June 2007 Diagnostic Pathology 2007, 2:19 doi:10.1186/1746-1596-2-19 This article is available from: /content/2/1/19 ? 2007 Martorell et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Extrapleural Solitary Fibrous tumors (SFTs) have been increasingly reported. The retroperitoneum, deep soft tissues of proximal extremities, abdominal cavity, trunk, head and neck are the most common extraserosal locations reported. Microscopically they show a wide range of morphological features, and so the differential diagnosis is extensive. Immunohistochemically, they commonly express CD34, vimentin, bcl-2 and CD99. Epithelial membrane antigen (EMA) and smooth muscle actin (SMA) may occasionally be expressed. Epithelioid morphology in extrapleural SFT has only very occasionally been described (five cases reported), some of them with biphasic pattern and others with malignant characteristics. Case presentation: A SFT of the thigh with epithelioid areas in a 63 year old woman is reported. Microscopically the tumor showed areas hypo and hipercellular.