以皮角为表现的肾透明细胞癌皮肤转移1例.pdfVIP

2012句õ8J1 t副4_~在他品专念念 第26卷第8期 Allg.2012 , Vo l.26 , No.8 J OORm vonOROOL 以皮角为表现的肾透明细胞癌皮肤转移 1 例 张芳芳，刘碍，史晓蔚，胡楠，左中，罗平 [摘要] 患者男，55 岁。右枕垂~红祷色皮角样培生物 3 个月，进行拉得大 1 个月。 2010 年确诊为肾癌并行右 肾摘除术。皮肤科情况:右枕部可见一长约 2.0cm 圆锥形红祸色增生物，顶部球状角化，外观似跳棋 状，基底部直径约 O. 8cm ，质硬，皮损周围红肿。皮损组织病理示:顶端表面破溃结疵，肉芽组织增生， 真皮浅层见结节状肿瘤组织，肿瘤由巢状、腺泡状透明细胞构成，细胞核轻度异型，细胞巢周围可见丰 富的血窦及毛细血管。免疫病理示:EMA( +) , CD lO( +) ,vimentin( +) ,CK7( -) , CK20( -)。诊断: 肾透明细胞癌皮肤转移。术后患者拒绝化疗，现仍在随访观察中。 [关键词] 皮肤转移;透明细胞癌;肾 [申图分类号] R737.11;R739.5 [文献标识码] B [文章编号] 1001 -7089(2012)08 -0741 -02 A Case of Menifestation as Cutaneous Horn Due to Clear Cell Carcinoma of Kidney Metastatic to Skin ZHANG Fang-fang , LlU Hlli , SHI Xiao-wei , HU Nan , ZUO Zhong , LUO Ping (Department 01 Dermatology , 210 Hospital 01 Peοple s Liberω， ion Army ,Dalian 116021 ,Chinα) [ Corresponding author] LIU Hui , E-mail: liuhuipf@ [Abstract] A 55-year-old male had presented with a red-brown cutaneous hom-like proliferation on his right occipitalia for three months and the lump had progressive increasing for one month. He was diagnosed kidney cancer in 2010 甜d his right kidney was resected. Physical examination showed one sorrel p日ffiness on patient s right occipitalia about 2. Ocm in height ,0. 8cm in basal diameter , spherical keratinization on the top , look like the draughts ,firm and red and swollen around the skin lesion. Histopathology showed the rupture and scab on the top surface , the proliferation of granulation tissue and nodosity tumor tissue in the superfi