石刁柏化学成分研究.pdfVIP

2016 年 12 月第18 卷第12 期 中国现代中药 Mod Chin Med Dec. 2016 Vol. 18 No. 12 ·基础研究· 石刁柏化学成分研究A 吴燕红1 ，肖兵2 ，付辉政l ，许新1 • (1.江西省药品检验检测研究院江西省药品与医疗器械质量工程技术研究中心，江西 南昌 33∞29; 2. 江西省林业科学院，江西 南昌 33∞32) [搞要] 目的:对石刁柏的 70% 乙醇水提取物的正丁醇部位进行化学成分研究。方法:采用硅胶、 Sephadex LH-20 以及 MPLC 等色谱方法分离纯化，根据理化性质和谱学数据鉴定化合物的结构。结果:从石刁柏中分离得到 7 个化合物，分别鉴定为: 1-0-反式对香豆耽甘油(1) 、 1-0-顺式对香豆酷甘泊(2) 、 2-苯乙基-O-ß-D-毗喃葡萄糖昔 (3) 、 6-0-L-毗喃阿拉伯糖基-β-D-p比喃葡萄糖昔(4) 、咖啡酸(5 )、懈皮素(6) 、苯乙醇(7) 。结论:化合物 1 -4 均 为首次从该植物中分离得到。 [关键词] 石刁柏;百合科;化学成分 Phytochemical Study of As严uagus officinalis wu Yanhong 1 , XIAO Bing 2 , FU Huizheng 1 , XU Yan1 拿 (1. liangxi Provincial Research lnstitutefor Drug Control , liangxi Prω， incial Engineering Research Centerfor Drug and Medical Device Quality , Nanchang 33∞29 ， China; 2. liangxi Academy of Forestry , Nanchαng 330032 , China) [ Abstract ] Objec创刊: To study the chemical constituents of n-butyl extract of Asparagus o.lfu:inalis. Methods: Isolation and purification of the compounds were carried out by silica gel , Sephadex LH -20 , MPLC chromatographies , and then the structures were identified according to the physical and chemical properties and various spectroscopic methods. Results: Seven compounds were identified as follows: 1-0-trans-p-coumaroylglycerol ( 1 ), 1-0-cis-p- coumaroylglycerol(2) , 2-phenylethyl-0-ß-D-glucopyranoside (3) , 6-0-L-arabinopyranosyl，β-D-glucopyranoside ( 4 ), caffeic acid ( 5) , quercetin ( 6) , and phenylethyl alcohol ( 7 ). Conclusion: The compounds 1 , 2 , 3 , and 4 were first isolated from this plant. [ Keywords] Asparlαgω