猪戊型肝炎病毒防控与研究策略分析.PDF

微生物学通报 JAN 20, 2009, 36(1): 130~133 Microbiology © 2009 by Institute of Microbiology, CAS tongbao@ 专论与综述 猪戊型肝炎病毒防控及研究策略分析 1,2* 3 1,2 1,2 1,2 李 震 陆海平 董世娟 朱于敏 于瑞嵩 (1. 201106) (2. 201106) (3. 201611) 摘 要: 戊型肝炎为人畜共患病病原, 猪是主要的病毒储库。我国猪场戊肝病毒流行情况复杂, 猪 感染率高, 同一地点存在3 型或/和4 型两种基因型混合污染。病毒存在基因重组和准种现象, 为 病毒遗传进化提供了遗传基础。当前猪戊肝感染人的主要媒介为污染的猪肉及其制品, 其他感染 机制和途径还有待进一步阐明。应加强对猪HEV 与猪场其他流行病原体相互关系的研究, 同时应 加强猪HEV 相关信息的积累分析包括对猪HEV 感染特性和遗传特性进行实时监测, 将猪HEV 流 行情况纳入兽医公共卫生预警体系, 实现常态跟踪。 关键词: 戊型肝炎, 猪, 流行状况, 防控策略 Research and Control Strategy of Swine Hepatitis E Virus in China LI Zhen1,2* LU Hai-Ping3 DONG Shi-Juan1,2 ZHU Yu-Min1,2 YU Rui-Song1,2 (1. Institute of Animal Sciences and Veterinary Medicine, Shanghai 201106, China) (2. Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai 201106, China) (3. Songjiang Institute of Veterinary Hygiene Supervision, Songjiang District, Shanghai 201611, China) Abstract: Hepatitis E, a newly emerging zoonotic infectious disease, is of major public health concern worldwide. Its pathogen is hepatitis E virus (HEV), which is in most cases enterically transmitted. Pigs are regarded as the major virus reservoir. The epidemic state of the disease is complicated in China. There exist