血培养阳性病原菌种类及耐药性监测分析.docVIP

血培养阳性病原菌种类及耐药性监测分析 　　[摘要] 目的 监测分析血培养阳性病原菌种类及耐药性。方法 整群收集该院2014年8月―2016年7月期间的 3459份血培养标本，分析总结血液培养阳性病原菌种类及耐药性。 结果 3 459份血培养标本中有400份鉴定结果呈阳性，其中革兰阳性细菌231份，占57.75%；革兰阴性细菌153份，占38.25%；真菌16份，占4.00%。葡萄球菌和肠球菌中未发现对替考拉宁及万古霉素的耐药株；但是肠杆菌科细菌对碳青霉烯类的抗菌药有着较高的敏感度。结论 血培养中检出的病原菌种类复杂，主要为革兰阳性细菌和革兰阴性细菌，且耐药性差异较大，临床应根据药敏结果科学用药，以减少多药耐药菌的发生 [关键词] 血培养；阳性病原菌；耐药性 [中图分类号] R44 [文献标识码] A [文章编号] 1674-0742（2017）04（a）-0120-03 7 Analysis of Blood Culture Positive Pathogenic Bacteria Species and Drug-resistant Monitoring ZHANG Hui-hua， WANG Li Department of Clinical Laboratory， Guangzhou 12th Peoples Hospital， Guangzhou， Guangdong Province， 510000 China [Abstract] Objective To monitor and analyze the blood culture positive pathogenic bacteria species and drug-resistance. Methods 3 459 blood culture samples in our hospital from August 2014 to July 2016 were collected and the blood culture positive pathogenic bacteria species and drug-resistance were analyzed and summarized. Results Group selection the 3 459 blood culture samples， 400 samples were positive， including 231 samples of gram positive bacteria， accounting for 57.75% and 153 samples of gram negative bacteria， accounting for 38.25%， and 16 samples of funguses， accounting for 4.00%， no strains of staphylococcus and enterococcus resistant to teicoplanin and vancomycin was found but the sensitivity of enterobacteriaceae bacteria. Conclusion The pathogenic bacteria species tested by the blood culture is complex， mainly including gram positive bacteria or gram negative bacteria， and the drug-resistance difference is big， in clinic， we should conduct the scientific medication according to the drug sensitive results in order to reduce the occurrence of multidrug resistant organisms. [Key words] Blood culture； Positive bacteria； Drug resistance 抗菌药物的广泛使用，以及抗感染治疗的不规范、不合理，易导致菌群失调，诱导病原菌耐药基因的表达，使患者病情不能得到有效控制，从而危及患者生命安全[1-2]。实验室的检测报告对抗生素的正确使用有巨大的参考价值，血培养作为目前诊断血流感染的主要方法，临床意义重大[3]。该文对该院2014年8―2016年7月期间的 3 459份标本进行血培养，监测分析血培养阳性病原菌种类及耐药性，现报