下鼻甲黏膜切开术治疗变应性鼻炎.pdfVIP

第21卷第6期 山东大学耳 鼻喉 眼学报 Vo1．21 No．6 2007年12月 J OTOLARYNGOL OPHTHAL SHANDONG UNIV Dec．2Oo7 文章编号：1673—3770(21307)06—0540～02 下鼻甲黏膜切开术治疗变应性鼻炎 徐福杰 ，林志娟 ，秦浩 (1．昌邑市人民医院耳鼻咽喉科，山东 昌邑261300；2．潍坊医学院分子免疫学研究所， 山东潍坊261042；3．潍坊医学院预防医学系，山东潍坊261042) 摘要：目的 探讨常年变应性鼻炎及并发支气管哮喘患者行下鼻甲黏膜切开术的疗效。方法 对72例 常年变应性鼻炎患者施行下鼻甲黏膜切开术，采用等级资料的秩和检验分析术后3个月及1年的疗效，采用 配对资料的t检验分析手术前后1年支气管哮喘的发作时间。结果 随访3个月显效66例，有效5例，无 效1例；随访1年显效28例，有效35例，无效9例；差异有统计学意义(Mann—Whitney M=1 219，P0．01)。 12例合并有支气管哮喘者1年发作哮喘的总时间术后为(71．66±63．26)h，术前为(89．25±75．65)h，差异有 统计学意义(t=2．96，P=0．01)。结论 下鼻甲黏膜切开术治疗常年变应性鼻炎在短期内有一定疗效，随 时间延长效果减弱，对合并支气管哮喘者有一定疗效。 关键词：鼻炎，变应性，常年性；哮喘；下鼻甲；外科手术 中图分类号：R765．21 文献标志码：A Inferior turbinate mucosa section for allergic rhinitis XU Fu-jie ，LIN Zhi-juan2，QIN m03 (1．Department of Otolaryngology，Changyi People S Hospital，Weifang 261300，Shandong，China； 2．Institute ofMolecular Immunology，Weifang Medical College，Weifang 261042，Shandong，China； 3．Department of Preventive Medicine，Weifang Medical College，Weifang 261042，Shandong，China) Abstract：Objective To explore the treatment method of perennial allergic rhinitis．Methods 72 patients with perennial allergic rhj tis had inferior turbinate mucosa section performed．The rank—silln test ofranked data was used to analyze the curative effect at 3 months and 1 year after the operations，the t-test of pairing data Was used to analyze the stroke time of bronchial asthlna 1 year before and after the operations．Results Followed up for 3 months．66 patients had excellent effect，5 had effect and 1 had no effect．Followed up for 1 year，28 patients had excellent effect，35 had ef- fect and 9 had no effect．The difference Was statistically significant(M=1 219，P0．01)．In 12 patients combined with bronc