小细胞肺癌3种化疗方案的成本-效果分析.pdfVIP

昆 明医学院学 报 2007，(6)：99～102 CN 53—1049／R Journ~ of Kunming Medical College 论 著 小细胞肺癌3种化疗方案的成本一效果分析 陈世灵，吴映蓉 (昆明医学院第三附属医院药剂科，云南昆明 650118) [摘要]日的 应用药物经济学分析方法评价小细胞肺癌3种化疗方案的成本一效果．方法 55例小细胞 肺癌患者随机分为3组：CAV方案、PE方案、GP方案组，运用药物经济学的成本～效果分析方法进行评价 结果 3种化疗方案中CAV方案有效率为5O％，1个疗程费用为340．76元，有效率每增加1个百分点，成本 为6 82元；PE方案有效率为71．9％，1个疗程费用为755．26元，有效率每增加 1个百分点，成本为1O．5元； GP方案有效率为85．7％，1个疗程费用为12 372．04元，有效率每增加1个百分点，成本为144．36元．结论口 PE方案是3种化疗方案中最为合理的方案． [关键词]成本一效果分析；小细胞肺癌；CAV方案；PE方案；GP方案 [中图分类号]R453[文献标识码]A [文章编号]1003—4706(2007)06—0099—04 Cost-effect Analysis of 3Types of Chemotherapy Schemes for SmallCell Lung Cancer CHEN Shi-ling，WU Ying—rong (Pharmaceutical Department of The Third AffiliatedHosp ital of Kunming Medical College，Kunming 65oll8．China) [Abstract]Objective To analyze the Cost-effect of small cell lung cancer by drug economics．Methods 55 patients of small cell lung cancer were devided into 3 groups， CAV，PE and GP scheme， we evaluated the cost and effect based on drug economics．Results The effectiveness rate of CAV was 50％，the cost of CAV was 340．76 yuan(RMB)，the cost of 1％increasing ofeffectiveness ratewas 6．82 yuan(RMB)；The effectiveness rate ofPEwas 71．9％，the cost ofPEwas 755．26 yuan(RMB)，the cost of 1％inc~asing of effectiveness rate Was 10．5 yuan(RMB)；The effectiveness rate of GP was 85．7％．the cost of GP was 12 372．04 yuan (RMB)，the cost of 1％increasing ofeffectiveness rate was 144．36 yuan(RMB)．Conclusion PE is the most reasonable chemotherapy scheme for small cell lung cancer． [Keywords]Cost—effect analysis；Small cell lung cancer；Chemotherapy scheme 恶性肿瘤 (癌症)是严重危害人类生命及健