细胞膜水通道（Cell membrane water channel）.docVIP

细胞膜水通道（Cell membrane water channel） Membrane water channel, ion channel structure and mechanism study In 2003, two American scientists won the Nobel Prize in chemistry for their discovery of water channels in cell membranes and the groundbreaking contributions to the structure and mechanism of ion channels. They won the Nobel Prize for chemistry rather than physiology or medicine because: A. their research is related to chemicals B. Their research is conducive to the development of drugs for some neurological diseases and diseases C. Their research goes deep into molecules, at the atomic level D. Their research goes deep into the cellular level C. their research into the molecular and atomic level level can go deep into the cells of the biology research, and micro levels (molecules or atoms) belong to the category of chemical research, water channel is the study of the structure and mechanism, it involves the specific molecular structure and properties, as well as the intermolecular interaction mechanism, so get the prize for chemistry The chemical nature of calcium channel is protein, called carrier. The calcium ions are transferred with the carrier. This protein binds to calcium ions like enzymes and substrate. The theory of the combination of enzymes and substrates: one, the key theory: the theory of the specificity of enzymes is obsolete, but the explanation is very good. 1. Enzyme activity center: the direct contact and action of the enzyme and substrate. In general, the substrate is much smaller than the enzyme. 2. The key theory: the center of the enzyme activity of conformation and structure of the substrate (shape) is complementary, like locks and keys is matching the rigidity, enzyme active center here compared to the key, the substrate to lock. On the basis of this theory, a three-point attachment theory is derived to explain the stereospecificity of enzymes. This is a theory proposed to correct the deficiency of key theory. It is believed that the struct