18～35岁年轻肥胖者心电学指标探析.docVIP

18～35岁年轻肥胖者心电学指标探析【摘要】 目的 探讨18～35岁中心型肥胖者与QT离散度及ST-T改变的心电学指标的关系。方法 对年龄18～35岁的39例单纯性中心型肥胖者（肥胖组）与34例正常体质量者（对照组）进行12导联同步心电图记录及测量QT离散度（QTd）、校正后QT离散度（QTcd）、ST段及T波、血压、体质量指数（BMI）、腰臀比（WHR）。结果 肥胖组的BMI、WHR、QTd、QTcd 均增大，与对照组比较差异有统计学意义（P0．01），且肥胖组出现ST-T改变的病例中QTd增大更明显。结论 年轻中心型肥胖者的QTd增大，尤其是伴有ST-T改变者中QTd增大更显著，提示心肌细胞电生理活动明显异常，并提出心电学指标有可能作为早期预测肥胖者具有较高患心血管病风险的一项参考指标。? 【关键词】年轻; 中心型肥胖; QT离散度; ST-T?? A study on the relationship between obesity youth aged from 18 to 35 and the electrocardiographic index ZHANG Qin, WAN Li-kai,TANG Wen-hong, et al. The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021,China? 【Abstract】 Objective To explore the relationship between the central obesity Youth aged from 18 to 35 years old and the electrocardiographic index such as the QT dispersion (QTd) and ST-T changing.Methods To measure the electrocardiogram of 12 leads, QTd, QTcd,ST segment, T wave, blood pressure, body mass index (BMI) and waist-hip ratio (WHR) in 39 patients with central obesity (obesity group) and 34 normal weight healthy subjects (control group), whose ages are all from 18 to 35 years old.Result The BMI,WHR,QTd,QTcd of the obesity group were higher than the normal group, with a significant difference comparied to the normal group (P0．001), and QTd were more larger in the obesity group patients with ST-T changing.Conclusion QTd of the central obesity youth are over the normal reference value, especially QTd of those with ST-T changing increaseing more significantly.The result indicates that the eletrophiological activity of the myocytes is significantly abnormal and the electrocardiographic index would be a reference index which could forecast the risk of the Cardiovascular Disease in obesity.? 【Key words】 Youth; Central Obesity; QT dispersion; ST-T ? 中国儿童及青少年的肥胖问题日益突出，肥胖是心血管疾病的高危因素。QT离散度、ST-T是反映心肌电生理活动的无创性检测方法，对预测心血管疾病的发生有重要价值。目前儿童及青少年与QTd的关系国内外已有相关报道[1] [2]，但QTd、ST-T这两个指标与18～35岁年轻肥胖者有何关系未见相关报道。为此笔者通过对18～35岁年轻肥胖者与心电学指标进行研究，现报告如下。? 1 资料与方法?