cardiovascular outcomes in patients with normal and abnormal 24-hour ambulatory blood pressure monitoring心血管结果正常和异常的患者24小时动态血压监测.pdfVIP

SAGE-Hindawi Access to Research International Journal of Hypertension Volume 2011, Article ID 786912, 4 pages doi:10.4061/2011/786912 Research Article Cardiovascular Outcomes in Patients with Normal and Abnormal 24-Hour Ambulatory Blood Pressure Monitoring P. Iqbal and Louise Stevenson Chesterfield Hypertension Clinic, Chesterfield Royal Hospital NHS Foundation Trust, Chesterfield S44 5BL, UK Correspondence should be addressed to P. Iqbal, drpi2pc@ Received 11 September 2010; Accepted 7 November 2010 Academic Editor: Samy I. McFarlane Copyright © 2011 P. Iqbal and L. Stevenson. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. 24-hour ambulatory blood pressure monitoring (ABPM) plays an important role in assessing cardiovascular prognosis, through presence or absence of ABPM-related prognostic features. Objectives. To study relationship between 24-hour ABPM and cardiovascular outcomes in patients from Chesterfield Royal Hospital. Material and Methods. Over 12 months from the 1st of August 2002, 1187 individuals had 24-hour ABPM performed. Cardiovascular outcomes were studied in a subset (297) of the original cohort, made up by every 4th consecutive subject. The following ABPM-related prognostic features were studied—high day time systolic and diastolic BP (≥135, ≥85 mmHg), high night time systolic and diastolic BP (≥120 mmHg, ≥75 mmHg), absence of nocturnal dip (≤10% fall in night time SBP), high early morning SBP (≥140 mmHg), and morning surge (≥20/15 mmHg). The cardiovascular outcomes studied in the fourth table included fatal and nonfatal MI, new diagnosis of angina,