effect of antihypertensive drug therapy on the blood pressure control among hypertensive patients attending campus’ teaching hospital of lome, togo, west africa抗高血压药物治疗对高血压患者血压控制参加校园的西非多哥洛美的教学医院,,.pdfVIP
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effect of antihypertensive drug therapy on the blood pressure control among hypertensive patients attending campus’ teaching hospital of lome, togo, west africa抗高血压药物治疗对高血压患者血压控制参加校园的西非多哥洛美的教学医院,,
Pharmacology Pharmacy, 2012, 3, 214-223
/10.4236/pp.2012.32029 Published Online April 2012 (http://www.SciRP.org/journal/pp)
Effect of Antihypertensive Drug Therapy on the Blood
Pressure Control among Hypertensive Patients Attending
Campus’ Teaching Hospital of Lome, Togo, West Africa
1 1 1 2 1
Yao Potchoo , Edem Goe-Akue , Findibe Damorou , Barima Massoka , Datouda Redah ,
Innocent P. Guissou3
1University of Lome, Mixed Faculty of Medicine and Pharmacy, Lome, Togo; 2University of Lome, School of Medical Assistants,
3
Lome, Togo; University of Ouagadougou, UFR/SOH, Laboratory of Pharmacology/Toxicology, Ouagadougou, Burkina Faso.
Email: ypotchoo@
Received January 17th, 2012; revised February 24th, 2012; accepted March 6th, 2012
ABSTRACT
High blood pressure (HBP) is a health problem world-wide. In Togo, that affection constitutes a more and more pre-
occupying cause of morbidity and mortality. This study is a prospective one which intended to identify the antihyper-
tensive regimens prescribed and evaluate their effect on patients’ blood pressure (BP) control. Out of the 204 patients
enrolled (mean: 55.01 12.55 years; sex ratio: 1.3), 112/176 placed on antihypertensive therapy have controlled their
BP (38.39% outpatients vs 61.61% inpatients). Related to the sex factor, we didn’t observe any significant difference in
the BP control. Whereas, the mean median value of BP reduction of outpatients (30.00/15.00 mmHg) (p = 0.001) was
half lower than that of inpatients (60.00/30.00 mmHg (p = 0.004)). Thirty five outpatients (81.40%) vs 64 inpatients
(92.75%) were placed on combination therapy. The bitherapy was prescribed to 23 outpatients (53.49%) against 27 in-
patients (39.13%) while the quadritherapy and more than 4 drugs combination were prescribed exclusively to inpatients
(20.29%, n = 14). That quadritherapy induce
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