effective therapeutic feeding with chickpea sesame based ready-to-use therapeutic food (cs-rutf) in wasted adults with confirmed or suspected aids基于有效的治疗性喂养鹰嘴豆芝麻即食治疗食物(cs-rutf)浪费了成年人确诊或疑似艾滋病.pdfVIP

World Journal of AIDS, 2011, 1, 169-181 169 doi:10.4236/wja.2011.14025 Published Online December 2011 (http://www.SciRP.org/journal/wja) Effective Therapeutic Feeding with Chickpea Sesame Based Ready-to-Use Therapeutic Food (CS-RUTF) in Wasted Adults with Confirmed or Suspected AIDS 1,2 3 1 1 Paluku Bahwere , Hedwig Deconinck , Theresa Banda , Steve Collins 1Valid International, Oxford, UK; 2School of Public Health, Free University of Brussels, Brussels, Belgium; 3Save the Children, Westport, USA. E-mail: {paluku, theresa, steve}@, hdeconinck@ Received September 1st, 2011; revised October 7th, 2011; accepted October 23rd, 2011. ABSTRACT Wasting has been observed as a common feature of the human immunodeficiency virus (HIV) disease since the first reports and its presence increases the risk of death. There is no consensus on how to manage wasting associated with HIV. The goal of this study was to assess the effectiveness of a locally made Chickpea Sesame Based RUTF (CS-RUTF) in treating wasting associated with HIV in developing countries. Chronically sick adults from Mangochi Health District (Malawi) with wasting and confirmed or presumptive clinical diagnosis of HIV were recruited for the study. Subjects received a daily ration of 500 grams of CS-RUTF for 3 to 5 months. Nutrition status changes and mortality were used to assess the effectiveness of the intervention. There were 3 patterns of anthropometric responses continuous weight gain (WG), static weight (SW) and continuation weight loss ( WL). The distribution of the 3 patterns is 53.9% (82/ 154) for the WG pattern , 9.1% (14/ 154) for the SW pattern and 37.0% (57/ 154) for the WL pattern. For the WG pattern, the overall median weight gain was 4.6 (2.4 to 7.