速度向量成像技术评价肥胖者颈总动脉弹性探究.docVIP

速度向量成像技术评价肥胖者颈总动脉弹性探究[摘要] 目的 探讨速度向量成像（VVI）技术评价肥胖者颈总动脉（CCA）短轴方向管壁弹性的应用价值。 方法 选择健康志愿者30名，肥胖者40名，分别利用VVI技术分析右侧CCA管壁短轴方向二维图像上各节段的最大应变（Smax）以及最大应变率（SRmax），用以评价其血管壁弹性差异。 结果 与对照组相比，肥胖组颈总动脉IMT显著增厚，血管各壁的Smax、SRmax显著降低（P 0.05）。 结论 VVI技术可用于分析颈总动脉管壁弹性变化。VVI参数与IMT相结合利于全面评价颈总动脉的弹性状态。 [关键词] 速度向量成像；肥胖；颈总动脉；弹性 [中图分类号] R445.1 [文献标识码] A [文章编号] 1674-4721（2012）06（a）-0106-02 Study on elastic characteristics of common carotidartery wall in obesity with velocity vector imaging ZHANG Na1 YANG Zhihang2 MA Yudong3 1.Department of Electronic Diagnosis, Fengtian Hospital Affiliated to Shenyang Medical College, Shenyang 110024, China;2.Basic Medical College, Shenyang Medical College, Shenyang 110034, China;3.Intensive Care Unit, Fengtian Hospital Affiliated to Shenyang Medical College, Shenyang 11002, China [Abstract] Objective To explore the elastic parameters of common carotid artery (CCA) wall in short-axis orientation of obesity patients with velocity vector imaging (VVI). Methods Thirty normal people and 40 obesity patients were selected. Two-dimensional dynamic images of CCA were acquired in short-axis view with color Doppler ultrasound. Elastic parameters were analyzed in right CCA in multiple segments. Comparison of these parameters between the two groups was performed as well. Results Compared with Control group, intima-media-thickness (IMT) in obesity group was significantly thickened as well as the strain and strain rate was significantly lower (P 0.05). Conclusion The elastic characteristics of the CCA wall can be analyzed by VVI technique. Combining parameters of VVI with IMT, the vascular wall elastic state can be assessed more comprehensively. [Key words] Velocity vector imaging; Common carotid artery; Obesity; Elasticity 心血管病占我国致死疾病之首，其中有15%~20%合并有肥胖症。早期准确诊断亚临床动脉血管弹性功能改变，明确其与肥胖程度的相关性，对于预防心脑血管意外的发生具有重要意义。本研究应用速度向量成像（velocity vector imaging，VVI）技术，分析肥胖者颈总动脉（common carotid artery，CCA）短轴方向管壁弹性参数，并与健康志愿者进行比较，探讨肥胖与血管壁结构变化之间的关系，为心血管病的早期防治提供理论依据。 1 资料与方法 1.1 一般资料