超声微泡造影剂制备中乳化剂的选择.PDFVIP

中国医学影像技术 2005 年第 2 1 卷第 4 期 　Chin J Med Imaging Technol ,2005 ,Vol 2 1 ,No 4 5·01 · Choice of emul sif ier in the preparation of ultrasound contrast agent 1 1 2 1 1 Z H A N G X uej i ao , C H E N G Yongqi ng , L I L ij un , C H E N N a , L I U Yi nf eng ( 1. D ep a rtment of A p p l ie d Chem is t ry , S chool of S cience , N ort hw es te rn Poly technical uni vers i ty , X i’an 7 10072 , Chi na; ) 2. T he S econ d A f f i l i ate d H osp i t al of X i’an J i aotong Uni vers i ty , X i’an 7 10003 , Chi na [ Abstract] 　The p rep aration of ult rasound cont rast agent (U CA) by emul sion polymerization wa s st udied . The st udy focu s on t he selection of t he emul sifier which i s necessary in t he p rep aration . Then t he effect of t he emul sifier do se and ratio on t he μ exp eriment al result s wa s st udied . The microbubbles were p rep ared by t hi s met hod had a diamet er of 2 to 8 m , concent ra tion of 9 . 5 1 ×1010 / ml ,and t he monomer conver sion rat e wa s up to 7 1 % , wort hy of much more research . [ Key words] 　Emul sion polymerization ; Emul sifier ; Monomer conver sion ; Ult ra sound cont ra st agent s , microbubbles 超声微泡造影剂制备中乳化剂的选择 1 1 2 1 1 张雪娇 ,程永清 ,李丽君 ,陈 　娜 ,刘银凤 ( 1. 西北工业大学理学