review of pharmacological effects of antrodia camphorata and its bioactive compounds审查的药理作用antrodia camphorata及其生物活性化合物.pdfVIP

Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2011, Article ID 212641, 17 pages doi:10.1093/ecam/nep108 Review Article Review of Pharmacological Effects of Antrodia camphorata and Its Bioactive Compounds Madamanchi Geethangili and Yew-Min Tzeng Institute of Biochemical Sciences and Technology, Chaoyang University of Technology, Wufeng, Taiwan Correspondence should be addressed to Yew-Min Tzeng, ymtzeng@.tw Received 22 May 2009; Accepted 21 July 2009 Copyright © 2011 M. Geethangili and Y.-M. Tzeng. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Antrodia camphorata is a unique mushroom of Taiwan, which has been used as a traditional medicine for protection of diverse health-related conditions. In an effort to translate this Eastern medicine into Western-accepted therapy, a great deal of work has been carried out on A. camphorata . This review discusses the biological activities of the crude extracts and the main bioactive compounds of A. camphorata . The list of bioactivities of crude extracts is huge, ranging from anti-cancer to vasorelaxation and others. Over 78 compounds consisting of terpenoids, benzenoids, lignans, benzoquinone derivatives, succinic and maleic derivatives, in addition to polysaccharides have been identified. Many of these compounds were evaluated for biological activity. Many activities of crude extracts and pure compounds of A. camphorata against some major diseases of our time, and thus, a current review is of great importance. It is concluded that A. camphorata can be considered as an efficient alternative