spinal chondrosarcoma a review脊椎软骨肉瘤审查.pdfVIP

Hindawi Publishing Corporation Sarcoma Volume 2011, Article ID 378957, 10 pages doi:10.1155/2011/378957 Review Article Spinal Chondrosarcoma: A Review Pavlos Katonis,1 Kalliopi Alpantaki,1 Konstantinos Michail,1 Stratos Lianoudakis,1 Zaharias Christoforakis,1 George Tzanakakis,2 and Apostolos Karantanas3 1 University Hospital, University of Crete, Heraklion 711 10, Greece 2 Department of Histology, Medical School, University of Crete, Heraklion 710 03, Greece 3 Department of Radiology, University Hospital, University of Crete, Heraklion 711 10, Greece Correspondence should be addressed to Pavlos Katonis, katonis@hol.gr Received 6 September 2010; Accepted 3 January 2011 Academic Editor: Peter Houghton Copyright © 2011 Pavlos Katonis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Chondrosarcoma is the third most common primary malignant bone tumor. Yet the spine represents the primary location in only 2% to 12% of these tumors. Almost all patients present with pain and a palpable mass. About 50% of patients present with neurologic symptoms. Chemotherapy and radiotherapy are generally unsuccessful while surgical resection is the treatment of choice. Early diagnosis and careful surgical staging are important to achieve adequate management. This paper provides an overview of the histopathological classification, clinical presentation, and diagnostic procedures regarding spinal chondrosarcoma. We highlight specific treatment modalities and discuss which is truly the most suitable approach for these tumors. Abstracts and original articles in English investigating these tumors