the prevalence of fatigue following deep brain stimulation surgery in parkinsons disease and association with quality of life疲劳的患病率在帕金森病和脑深部电刺激术与生活质量.pdfVIP

Hindawi Publishing Corporation Parkinson’s Disease Volume 2012, Article ID 769506, 5 pages doi:10.1155/2012/769506 Clinical Study The Prevalence of Fatigue Following Deep Brain Stimulation Surgery in Parkinson’s Disease and Association with Quality of Life Benzi M. Kluger,1 Veronica Parra,1 Charles Jacobson,2 Cynthia W. Garvan,3 Ramon L. Rodriguez,2 Hubert H. Fernandez,2 Amanda Fogel,4 Barry M. Skoblar,4 Dawn Bowers,4 and Michael S. Okun2 1 Department of Neurology, University of Colorado Denver, P.O. Box 6511, Aurora, CO 80045, USA 2 Department of Neurology, University of Florida, Gainesville, FL 32610, USA 3 Department of Educational Psychology, University of Florida, Gainesville, FL 32611, USA 4 Department of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610, USA Correspondence should be addressed to Benzi M. Kluger, benzi.kluger@ Received 1 July 2011; Revised 6 March 2012; Accepted 6 March 2012 Academic Editor: Daniel H. Jacobs Copyright © 2012 Benzi M. Kluger et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fatigue is a common and disabling nonmotor symptom seen in Parkinson’s disease (PD). While deep brain stimulation surgery (DBS) improves motor symptoms, it has also been associated with non-motor side effects. To date no study has utilized standardized instruments to evaluate fatigue following DBS surgery. Our objective was to determine the prevalence of fatigue following DBS surgery in PD its impact on quality of life and explore predictive factors. We recruited 44 PD subjects. At least one year following DBS