原创力文档a review of the current treatment methods for posthaemorrhagic hydrocephalus of infants审查目前的治疗方法posthaemorrhagic脑积水的婴儿.pdfVIP
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a review of the current treatment methods for posthaemorrhagic hydrocephalus of infants审查目前的治疗方法posthaemorrhagic脑积水的婴儿
Cerebrospinal Fluid Research BioMed Central
Review Open Access
A review of the current treatment methods for posthaemorrhagic
hydrocephalus of infants
1 2 1
David Shooman* , Howard Portess and Owen Sparrow
Address: 1Department of Neurosurgery, Wessex Neurological Centre, Southampton General Hospital, Tremona Road, Southampton, Hampshire,
SO16 6YD, UK and 2Childrens X-Ray, Department of Radiology, Southampton General Hospital, Tremona Road, Southampton, Hampshire,
SO16 6YD, UK
Email: David Shooman* - shooman@.uk; Howard Portess - Howard.Portess@suht.swest.nhs.uk;
Owen Sparrow - Owen.Sparrow@suht.swest.nhs.uk
* Corresponding author
Published: 30 January 2009 Received: 14 September 2008
Accepted: 30 January 2009
Cerebrospinal Fluid Research 2009, 6:1 doi:10.1186/1743-8454-6-1
This article is available from: /content/6/1/1
© 2009 Shooman et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Posthaemorrhagic hydrocephalus (PHH) is a major problem for premature infants, generally requiring
lifelong care. It results from small blood clots inducing scarring within CSF channels impeding CSF
circulation. Transforming growth factor – beta is released into CSF and cytokines stimulate deposition of
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