原创力文档recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer a model of tumor-host interaction招聘和胰腺星状细胞激活的骨髓tumor-host胰腺癌模型的交互.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer a model of tumor-host interaction招聘和胰腺星状细胞激活的骨髓tumor-host胰腺癌模型的交互
Recruitment and Activation of Pancreatic Stellate Cells
from the Bone Marrow in Pancreatic Cancer: A Model of
Tumor-Host Interaction
1 1 1 1,2 3
Christopher J. Scarlett , Emily K. Colvin , Mark Pinese , David K. Chang , Adrienne L. Morey ,
1 1 4 1 1
Elizabeth A. Musgrove , Marina Pajic , Minoti Apte , Susan M. Henshall , Robert L. Sutherland , James
G. Kench1,5, Andrew V. Biankin1,2*
1 Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, Australia, 2 Division of Surgery, Bankstown Hospital, Eldridge Road, Bankstown,
Sydney, Australia, 3 Department of Anatomical Pathology, St Vincent’s Hospital, Darlinghurst, Australia, 4 South Western Sydney Clinical School, The University of New
South Wales, Sydney, Australia, 5 Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
Abstract
Background and Aims: Chronic pancreatitis and pancreatic cancer are characterised by extensive stellate cell mediated
fibrosis, and current therapeutic development includes targeting pancreatic cancer stroma and tumor-host interactions.
Recent evidence has suggested that circulating bone marrow derived stem cells (BMDC) contribute to solid organs. We
aimed to define the role of circulating haematopoietic cells in the normal and diseased pancreas.
Methods: Whole bone marrow was harvested from male b-actin-EGFP donor mice and transplanted into irradiated female
recipient C57/BL6 mice. Chronic pancreatitis was induced with repeat injections of caerulein, while carcinogenesis was
induced
您可能关注的文档
- randomized controlled trials of hivaids prevention and treatment in africa results from the cochrane hivaids specialized register随机对照试验的条件在非洲的预防和治疗结果cochrane条件专门登记.pdf
- randomized, controlled intervention trial of male circumcision for reduction of hiv infection risk the anrs 1265 trial随机对照干预试验的男性包皮环切术感染艾滋病毒的风险降低艾滋病1265试验.pdf
- randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and sp for malaria in pregnancy in tanzania随机试验的青蒿琥酯+阿莫地喹,磺胺多辛-乙胺嘧啶+阿莫地喹chlorproguanal-dapsone和sp疟疾在坦桑尼亚的怀孕.pdf
- rank and order evaluating the performance of snps for individual assignment in a non-model organism评估的性能等级和秩序snp对个人分配在non-model有机体.pdf
- ranking transitive chemical-disease inferences using local network topology in the comparative toxicogenomics database排名传递chemical-disease推断比较toxicogenomics数据库中使用本地网络拓扑.pdf
- randomized, placebo-controlled trial of mipomersen in patients with severe hypercholesterolemia receiving maximally tolerated lipid-lowering therapy随机、安慰剂对照试验mipomersen严重高胆固醇血症患者接受最大限度容忍降脂治疗.pdf
- rantes gene g-403a polymorphism and coronary artery disease a meta analysis of observational studies咆哮基因g - 403 a多态性和冠状动脉疾病的观察性研究的meta分析.pdf
- ranking candidate disease genes from gene expression and protein interaction a katz-centrality based approach排名候选致病基因的基因表达和蛋白质相互作用基于katz-centrality方法.pdf
- ranking malaria risk factors to guide malaria control efforts in african highlands排名疟疾风险因素指导在非洲高地疟疾控制工作.pdf
- rapamycin regulates the expression and activity of krüppel-like transcription factor 2 in human umbilical vein endothelial cells雷帕霉素调节kruppel-like转录因子的表达和活动2人类脐静脉内皮细胞.pdf
- recurrent activity in higher order, modality non-specific brain regions a granger causality analysis of autobiographic memory retrieval在高阶经常性活动,形态非特异性脑区自传记忆提取的格兰杰因果分析.pdf
- rectangular coordination polymer nanoplates large-scale, rapid synthesis and their application as a fluorescent sensing platform for dna detection矩形配位聚合物nanoplates大规模、快速的合成及其应用程序作为荧光传感平台进行dna检测.pdf
- recovering protein-protein and domain-domain interactions from aggregation of ip-ms proteomics of coregulator complexes恢复蛋白质的聚合和domain-domain交互ip-ms coregulator复合物的蛋白质组学.pdf
- recruitment of polo kinase to the spindle midzone during cytokinesis requires the feoklp3a complex招聘的马球激酶主轴midzone胞质分裂过程中需要feoklp3a复杂.pdf
- recruitment to the nuclear periphery can alter expression of genes in human cells招聘核外围可以改变人类细胞的基因表达.pdf
- recurrent genomic gains in preinvasive lesions as a biomarker of risk for lung cancer复发性基因在蔓延前的损伤的生物标志物患肺癌的风险.pdf
- recurrent dnmt3a r882 mutations in chinese patients with acute myeloid leukemia and myelodysplastic syndrome复发性dnmt3a r882突变在中国急性骨髓性白血病和骨髓增生异常综合征患者.pdf
- rectification of the water permeability in cos-7 cells at 22, 10 and 0°c整流cos-7透水性的细胞在22日10 0°c.pdf
- recursive cluster elimination based support vector machine for disease state prediction using resting state functional and effective brain connectivity疾病状态递归消除集群基于支持向量机预测使用大脑静息状态的功能和有效的连接.pdf
- recruitment of rad51 and rad52 to short telomeres triggers a mec1-mediated hypersensitivity to double-stranded dna breaks in senescent budding yeast招聘rad51和端粒短rad52触发mec1-mediated过敏症在衰老出芽酵母dna双链断裂.pdf
文档评论（0）