serum levels of tweak and scavenger receptor cd163 in type 1 diabetes mellitus relationship with cardiovascular risk factors. a case-control study血清水平的调整和清道夫受体cd163在1型糖尿病与心血管危险因素的关系。.pdfVIP

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serum levels of tweak and scavenger receptor cd163 in type 1 diabetes mellitus relationship with cardiovascular risk factors. a case-control study血清水平的调整和清道夫受体cd163在1型糖尿病与心血管危险因素的关系。.pdf

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serum levels of tweak and scavenger receptor cd163 in type 1 diabetes mellitus relationship with cardiovascular risk factors. a case-control study血清水平的调整和清道夫受体cd163在1型糖尿病与心血管危险因素的关系。

Serum Levels of TWEAK and Scavenger Receptor CD163 in Type 1 Diabetes Mellitus: Relationship with Cardiovascular Risk Factors. A Case-Control Study ´ 1 ´ ´ 1 ´ 2 ´ 1 Gemma Llaurado *, Jose-Miguel Gonzalez-Clemente , Elsa Maymo-Masip , David Subıas , 2 ´ 2 Joan Vendrell , Matilde R. Chacon * ´ ` ` ´ ` 1 Department of Diabetes, Endocrinology and Nutrition, Hospital de Sabadell, Corporacio Sanitaria i Universitaria Parc Taulı (Universitat Autonoma de Barcelona), Sabadell, ´ ´ ´ Spain, 2 Centro de Investigacion Biomedica en Red de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), Hospital Universitari Joan XXIII de Tarragona, Insitut Pere Virgili, Universitat Rovira i Virgili, Tarragona, Spain Abstract Objective: To test the usefulness of serum concentrations of tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) and soluble scavenger receptor CD163 (sCD163) as markers of subtle inflammation in patients with type 1 diabetes mellitus (T1DM) without clinical cardiovascular (CV) disease and to evaluate their relationship with arterial stiffness (AS). Methods: Sixty-eight patients with T1DM and 68 age and sex-matched, healthy subjects were evaluated. Anthropometrical variables and CV risk factors were recorded. Serum concentrations of sTWEAK and sCD163 were measured. AS was assessed by aortic pulse wave velocity (aPWV). All statistical analyses were stratified by gender. Results: T1DM patie