polyphenolic profile and bioactivity study of oenothera speciosa nutt. aerial parts纳特和生物活性研究月见草的叶多酚概要文件。.pdfVIP

Molecules 2009, 14, 1456-1467; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Polyphenolic Profile and Bioactivity Study of Oenothera speciosa Nutt. Aerial Parts Mohamed S. Marzouk 1,*, Fatma A. Moharram 2, Rabab A. El Dib 2, Siham M. El-Shenawy 3 2 and Ahmed F. Tawfike 1 Natural Products Group, Centre of Scientific Excellence, National Research Center, El-Behoos St. 31, Dokki, Cairo, Egypt 2 Department of Pharmacognosy, Faculty of Pharmacy, Helwan University, Cairo, Egypt; E-mails: famoharram1@ (F-A.M.); reldib@ (R-A.ED.); ahmedfares82@ (A-F.T.) 3 Department of Pharmacology, National Research Center, El-Behoos St.31, Dokki, Cairo, Egypt; E-mail: siham_elshenawy@ (S-M.ES.) * Author to whom correspondence should be addressed; E-mail: msmarzouk@yahoo.co.uk; Tel.: +962796334798; Fax: +20233388801. Received: 10 February 2009; in revised form: 19 March 2009 / Accepted: 26 March 2009 / Published: 7 April 2009 Abstract: Two new flavonol glycosides, myricetin 4-O-α-L-rhamnopyranoside (1) and quercetin 3-O-α-L-rhamnopyranoside (2), together with a novel biflavonol compound, speciin (3), as well as eleven phenolic metabolites, namely myricitrin (4), europetin 3-O-α- 1 L- C -rhamnopyranoside (5), quercitrin (6), hyperin (7), rhamnetin 3-O-β-galacto- 4 pyranoside (8), caffeic acid (9), caffeic acid methyl ester (10), chlorogenic acid (11), chloroge