prenylated xanthones from the bark of garcinia xanthochymus and their 1,1-diphenyl-2-picrylhydrazyl (dpph) radical scavenging activitiesprenylated氧杂蒽酮从藤黄属植物的树皮xanthochymus 1,1-diphenyl-2-picrylhydrazyl dpph自由基清除活性.pdfVIP

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prenylated xanthones from the bark of garcinia xanthochymus and their 1,1-diphenyl-2-picrylhydrazyl (dpph) radical scavenging activitiesprenylated氧杂蒽酮从藤黄属植物的树皮xanthochymus 1,1-diphenyl-2-picrylhydrazyl dpph自由基清除活性.pdf

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prenylated xanthones from the bark of garcinia xanthochymus and their 1,1-diphenyl-2-picrylhydrazyl (dpph) radical scavenging activitiesprenylated氧杂蒽酮从藤黄属植物的树皮xanthochymus 1,1-diphenyl-2-picrylhydrazyl dpph自由基清除活性

Molecules 2010, 15, 7438-7449; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Prenylated Xanthones from the Bark of Garcinia xanthochymus and Their 1,1-Diphenyl-2-picrylhydrazyl (DPPH) Radical Scavenging Activities Yu Chen 1,2,3, Hua Fan 4, Guang-zhong Yang 1,2,4,*, Yan Jiang 4, Fang-fang Zhong 4 and Hong-wu He 1,2,* 1 Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, Central China Normal University, Wuhan 430079, China 2 State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China 3 College of Chemistry and Material Sciences, South Central University for Nationalities, Wuhan 430074, China 4 Laboratory for Natural Product Chemistry, College of Pharmacy, South Central University for Nationalities, Wuhan 430074, China * Authors to whom correspondence should be addressed; E-Mail: yanggz888@126.com (G.-z.Y.); he1208@ (H.-w.H.); Tel.: 86-27- Fax: 86-27 Received: 25 September 2010; in revised form: 7 October 2010 / Accepted: 11 October 2010 / Published: 22 October 2010 Abstract: Garcinia xanthochymus has been widely used in traditional Chinese medicine for expelling worms and removing food toxins. Bioassay-guided fractionation of an EtOAc-soluble extract of G. xanthochymus stem bark led to the isolation of six new xanthones. Their structures were elucidated by spectroscopic methods, especially 2D-NMR techniques. Free-radical-scavenging activities