原创力文档synthesis and determination of pka values of some new 3,4-disubstituted-4,5-dihydro-1h-1,2,4-triazol-5-one derivatives in non-aqueous solvents合成和决心的pka的一些新的值3,4-disubstituted-4 5-dihydro-1h-1,2,4-triazol-5-one衍生品,非水溶剂.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
synthesis and determination of pka values of some new 3,4-disubstituted-4,5-dihydro-1h-1,2,4-triazol-5-one derivatives in non-aqueous solvents合成和决心的pka的一些新的值3,4-disubstituted-4 5-dihydro-1h-1,2,4-triazol-5-one衍生品,非水溶剂
Molecules 2004, 9, 232-240
molecules
ISSN 1420-3049
/
Synthesis and Determination of pKa Values of Some New 3,4-
Disubstituted-4,5-Dihydro-1H-1,2,4-triazol-5-one Derivatives in
Non-aqueous Solvents
Haydar Yüksek 1,*, Zafer Ocak 1, Muzaffer Alkan 1, Şule Bahçeci 3 and Mustafa Özdemir 2
1
Department of Chemistry, Kafkas University, 36100 Kars, Turkey; Fax (+90)-474-2121185.
2
Department of Chemistry, Karadeniz Technical University, 61080 Trabzon, Turkey.
3
Fatih Education Faculty, Karadeniz Technical University, 61335 Trabzon, Turkey.
*Author to whom correspondence should be addressed; e-mail: hyuksek98@
Received: 12 June 2002; in revised from: /Accepted: 11 March 2004 / Published: 31 March 2004
Abstract: 3-Alkyl(Aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) reacted with
2-furoyl chloride and thiophene-2-carbonyl chloride to afford the corresponding 3-
alkyl(aryl)-4-(2-furoylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (3) and 3-alkyl(aryl)-
4-(2-thienylcarbonylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (4), respectively. The
new compounds synthesized were characterized by using IR, 1H-NMR, 13C-NMR and
UV spectral data together with elemental analysis. In addition, to investigate the effects
of solvents and molecular structure upon acidity, compounds 3 and 4 were titrated
potentiometrically with tetrabutylammonium hydroxide in four non-aqueous solvents
(isopropyl alcohol, tert-butyl alcohol, N,
您可能关注的文档
- superoxide dismutase 1 and tgsod1g93a mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis超氧化物歧化酶1和tgsod1g93a小鼠脊髓种子纤维,建议在肌萎缩性脊髓侧索硬化症繁殖的细胞死亡的机制.pdf
- supercritical transesterification of palm oil and hydrated ethanol in a fixed bed reactor with a caoal2o3 catalyst超临界酯交换的棕榈油和含水乙醇caoal2o3催化剂的固定床反应器.pdf
- superoxide dismutase as a novel macromolecular nitric oxide carrier preparation and characterization超氧化物歧化酶作为一种新型高分子一氧化氮载体制备和表征.pdf
- superoxide enhances the antitumor combination of admnsod plus bcnu in breast cancer超氧化物增强的抗肿瘤结合admnsod + bcnu在乳腺癌.pdf
- superparamagnetic nanocomposites templated with pyrazole-containing diblock copolymers超顺磁的纳米复合材料模板化与pyrazole-containing diblock共聚物.pdf
- superparasitism in the fruit fly parasitoid diachasmimorpha longicaudata (hymenoptera braconidae) and the implications for mass rearing and augmentative release重寄生在果蝇拟寄生物diachasmimorpha longicaudata(膜翅目昆虫茧蜂科)和大规模饲养和扩大的释放的影响.pdf
- superstatistics and gravitationsuperstatistics和万有引力.pdf
- superposition of transcriptional behaviors determines gene state决定基因转录行为状态的叠加.pdf
- superspheres intermediate shapes between spheres and polyhedrasuperspheres中间形状的球体和多面体之间.pdf
- supersymmetric extensions of non-relativistic scaling algebras超对称扩展的非相对论扩展代数.pdf
- synthesis and dpph radical scavenging activity of prenylated phenol derivatives合成和dpph自由基清除活性prenylated酚衍生品.pdf
- synthesis and effect on human hepg2 cells of 1,2-bis- (2-methylallyl)disulfane对人类hepg2细胞合成和影响,以叔u2014u2014disulfane(2-methylallyl).pdf
- synthesis and electrophilic substitution of pyrido[2,3,4-kl]-acridines合成与亲电取代的pyrido[2、3、4-kl]-acridines.pdf
- synthesis and early development of hexadecyloxypropyl-cidofovir an oral antipoxvirus nucleoside phosphonate合成和早期发展hexadecyloxypropyl-cidofovir口服antipoxvirus核苷膦酸酯.pdf
- synthesis and evaluation of a conjugate vaccine composed of staphylococcus aureus poly-n-acetyl-glucosamine and clumping factor a合成和评价结合疫苗由金黄色葡萄球菌poly-n-acetyl-glucosamine和形成因素.pdf
- synthesis and crystal structure of a new triosmium alkylidyne carbonyl cluster containing a chiral ferrocenylphosphine ligand羰基合成和晶体结构的新triosmium alkylidyne集群含有一个手性ferrocenylphosphine配体.pdf
- synthesis and evaluation of a molecularly imprinted polymer for 2,4-dinitrophenol分子印迹聚合物的合成和评价2,4-dinitrophenol.pdf
- synthesis and evaluation of a molecularly imprinted polymer for selective solid-phase extraction of irinotecan from human serum samples分子印迹聚合物的合成和评价选择性固相萃取的伊立替康人的血清样本.pdf
- synthesis and characterization of anti-her2 antibody conjugated cdsecdzns quantum dots for fluorescence imaging of breast cancer cells合成和表征anti-her2抗体共轭cdsecdzns量子点荧光成像的乳腺癌细胞.pdf
- synthesis and evaluation of highly tolerant pd electrocatalysts as cathodes in direct ethylene glycol fuel cells (degfc)合成和评估pd高度宽容electrocatalysts在乙二醇直接燃料电池阴极(degfc).pdf
文档评论（0）