通过评价生存质量对比各种方法治疗晚期癌症疗效.docVIP

通过评价生存质量对比各种方法治疗晚期癌症疗效 　【摘要】 目的 编制中西医结合生存质量表，通过对提高中晚期胃癌患者生存质量，来评价中医、西医及中西医结合方法抗肿瘤的疗效。方法 (1)编制中西医结合生存质量表:在国内外较为通行认可的量表的基础上首次编制了更加完善的具有中西医结合特色的生存质量表。(2)应用该量表对比各种方法改善癌症患者生存质量的疗效：选择所收集的完成最终生存质量测评的478例患者，其中接受化疗的患者204例，中西医结合疗法的患者110例，中药疗法患者114例，地区中心医院共收集病例50例。根据各组治疗前后生存质量差值，归纳整理分析检验，比较各种方法对提高中晚期胃癌患者生存质量的疗效。结果 (1)经临床实践及统计学检验，该量表是可以试用于临床生存质量疗效评价的。(2)总体疗效最好，好转率最高，恶化率最低的是中药组，其次为中西医结合组，化疗组总体疗效最差。结论 本量表具有较好的临床实用性，能够全面地评价癌症患者治疗后的生存质量，从而反映了治疗后的疗效——中药抗肿瘤疗效显著，生存质量明显提高，生存期较长；而化疗药疗效最差，生存质量没有明显改善，生存期较短；中西医结合方法疗效的好坏，最关键在稳定期内治疗措施的选择，当化疗药与中药正确结合时，则起协同作用，反之则加速恶化。资料也表明，化疗组的稳定率最高，但稳定时间最短，稳定期过后最易恶化，生存期较短，而中药组则相反，稳定期过后多趋向好转，中西医结合组居中。 【关键词】 生存质量 中晚期胃癌 疗效 中医 中西医结合 西医 The therapeutic effect comparison of different methods to treatlate carcinoma by evaluation of patient life quality 　　【Abstract】 Objective To plait combination of TCM and western medicine QOL table and evaluation the effect of late phase carcinoma of stomach patient of QOL by this table.To plait the table to evaluation the effect of three methods antitumor by improving the QOL. Methods (1)First time to plait the combination of TCM and western medicine.QOL table Basing on the literature of interal and extra country about the measuring scale，revising and consurnmating step by step，plait the table with the Chinese medical science peculiarity，(2)Applying the table firstly comparised the effect of various kinds methods improving the patient’s QOL.The 478 patients was choosed，among them 204 patients were offered by chemotherapy.110 atients was offered combination of TCM and western medicine.114 patients offered the traditional Chinese medicine.All the patients filled in a form at pretreatment and post-treatment partly，based on the difference of QOL between the pretreatment and post-treatment，assembling analysing.Comparising the effect of various kinds methods rising stomach cancer QOL.Results (1)Statistics checks rudiment result makes clear that the table can be applied in clinical.(2)The traditional Chinese medicine’s population effect