金匮肾气丸对2型糖尿病胰岛素抵抗大鼠LEPTIN及肾脏组织形态学影响.pdf

金匮肾气丸对2型糖尿病胰岛素抵抗大鼠LEPTIN及肾脏组织形态学影响.pdf

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金匮肾气丸对2型糖尿病胰岛素抵抗大鼠LEPTIN及肾脏组织形态学的影响 ABSTRACT ofJinkuishen and tissue theeffects on the Objeetive:To explore qipill leptin kidney inT2DMratswithinsulinresistance. morphologicchanges Methods:70SPF Wistarratswhose wereabout selectedaS were grade weight 200_+209 the forthis halfwerethemaleandanotherhalfwerethe.female.After subjects study,a tothefoodfor1 ratswouldbeselected fromallofrats adapting week,8 randomly following astheblank 62ratswerefedwith their the weight group(ordinaryfeeO.Theremaining be and food.The6th ratswould high—fathigh-sugar week,62 undergo onceinIeRlower with enablethemto injection belly 35mg‘kg1streptozotocin(STZ),and becomeT2DMratswithinsulinresistance.The8th wouldselect50successful week,we animalmodelswhichweredivided intoamodle a randomly group、 Jinkuishen dose Jinkuishen mediumdose group、a qipill(J均highgroup、a qipill group andJinkuishen lowdose 13th wouldexecuteallofratsand week,WC qipill group.The selectthebloodserumswhichweretestedfortheblood INS,ISI,TC, glucose,LEP, TG、HDL-Candobservedthe tissue ’

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