氟康唑眼浴及滴眼联合斯皮仁诺治疗真菌性角膜溃疡疗效观察.docVIP

氟康唑眼浴及滴眼联合斯皮仁诺治疗真菌性角膜溃疡疗效观察 　【关键词】 氟康唑；,,眼浴；,,斯皮仁诺；,,真菌性角膜溃疡 　　摘要：目的：观察氟康唑眼浴及滴眼联合斯皮仁诺治疗真菌性角膜溃疡的疗效。方法：临床确诊为真菌性角膜溃疡19例。轻度：0.2%氟康唑眼浴30min，每日3次，滴0.2%氟康唑滴眼液，1次/h，联合溃疡面涂斯皮仁诺粉剂，qod；中度：0.2%氟康唑眼浴45min，每日3次，滴0.2%氟康唑滴眼液，1次/30min，联合溃疡面涂斯皮仁诺粉剂qod，必要时斯皮仁诺200mg睡前服；重度：0.2%氟康唑眼浴1h，每日2次，滴0.2%氟康唑滴眼液，1次/10min，联合溃疡面涂斯皮仁诺粉剂qod，斯皮仁诺300mg睡前服。视病情好转适当调整眼浴次数及滴眼次数，减少口服服量。结果：19例患者中，16例治愈(84.21%)，3例好转(15.79%)。结论：氟康唑眼浴及滴眼联合斯皮仁诺治疗真菌性角膜溃疡疗效好，作用快，治疗方便，痛苦小，无明显副作用。 　　关键词： 氟康唑； 眼浴； 斯皮仁诺； 真菌性角膜溃疡 　　Observation for the Curative Effect of Healingn Mycotic Corneal Ulcer by Fukangzuo Eye Bath and Eye-dripping Sipirenuo 　　　Abstract：Objective：To observe the curative effect of healing mycotic corneal ulcer by Fukangzuo eye bath and eye-dripping Sipirenuo.Method：Here are 19 cases who are diagnosed as mycotic corneal ulcer.For the light patients：having an eye bath using 0.2% Fukangzuo three times one day and then dripping 0.2% Fukangzuo for 30minutes one time one hour，combining using Sipirenuo power，qod；for the middle-degree：having an eye bath using 0.2% Fukangzuo 45 minutes three times one day and then dripping 0.2% Fukangzuo one time half an hour，combining using Sipirenuo power，qod，if necessary，taking 200mg Sipirenuo before sleeping；for the severe：having an eye bath using 0.2% Fukangzuo one hour two times one day and then dripping 0.2% Fukangzuo one time ten minutes，combining using Sipirenuo power，qod，taking 300mg Sipirenuo before sleeping.When the disease gets better，properly adjusting the bath time and dripping time and increasing the dose of oral taking.Result：For the 19 cases，16（84.21%）are cured and 3（15.79%）are better.Conclusion：Fukangzuo eye bath and eye-dripping Sippirenuo have a perfect curative effect for healing mycotic corneal ulcer.It acted fast and the pain is less.The treatment is easy to do and there is no obvious side effect. 　　Key words： Fukangzuo； Eye bath； Sipirenuo； Mycotic corneal ulcer 　　真菌性角膜溃疡是由真菌感染所致的一种致盲率很高的疾患，主要致病菌为曲霉菌，白色念珠球菌、镰刀菌、青霉菌、酵母菌等［1］。眼角膜的生产性外伤为真菌的感染提供了机会，抗生素、皮质激素及抗病毒药物的广泛应用，角