山莨菪碱合用非那根治疗眩晕症176例临床对照观察.docVIP

精品论文 参考文献 山莨菪碱合用非那根治疗眩晕症176例临床对照观察 廖纪华 （东莞市长安医院急诊科 广东东莞 523843） 【摘要】目的 观察山莨菪碱（654-Ⅱ）合用非那根治疗眩晕症的临床疗效。 方法 351例病人随机分成2组，治疗组176例，使用山莨菪碱注射液10-20mg/d，非那根注射液25-50mg/d，肌注，疗程3天；对照组175例，使用盐酸倍他司汀注射液500ml/d，静脉滴注，疗程3天。观察两组的总有效率。结果 治疗组总有效率91.5%（161例），对照组总有效率78.9%（137例）。结论 山莨菪碱合用非那根治疗眩晕症有明显效果（P＜0.05），优于倍他司汀。 【关键词】 眩晕症 山莨菪碱 非那根 倍他司汀 【中图分类号】R453 【文献标识码】A 【文章编号】2095-1752（2013）29-0232-02 Clinical comparative observation on curative effect of Anisodamine combinded with phenergan in treating vertige. Liao jee-hua . Department of Emergency .the Changan`s Hospilal of Dongguan City Dongguan 523843 Guangdong.china. 【Abstract】 object To compare the effect between Anisodamine cambinded with phenergan and Betahistine in treating vertige . Methods 351 Patients of vertige were ennelled in the this study and were divided two groups, the freapeutic gneup(176 patients) were treated with Anisodamine(10-20mg/d) and Phenergan(25-50mg/d) intramuscular..injection for 3days. While control groups(175 Patients) were treated with Betahistine infravenuccs injection for 3 days The general effectic rate of the two were observed and conpared. Result. The general effectic rate was 91.5%(161). in ehe therapeetic group and 78.9%(137) in the control group and there was signifient difference between the two group (P＜0.05). Conclusion The Anisodamine combined with phenergan had better curative effect than Betahistine injection in treatment of vertigc. 【key words】vertigc Anisodamine phenergan Betahistine 眩晕症是门急诊神经内科的常见多发病症[1]，病因复杂，治疗各异，笔者从事神经内科近三十年，应用山莨菪碱合用非那根注射液治疗眩晕，尤其对某些发作性重症病例快速有效，副作用少，经济，现将本项临床观察总结分析如下： 1. 资料与方法 1.1. 一般资料 收集2010.1—2012.4月门、急诊及住院以眩晕为主诉病例351例（除外出血病例）。其中高血压74例，椎基底动脉供血不足64例，颈椎病56例，美尼尔氏、前庭神经元、内耳眩晕症52例，药物或中毒性38例，偏头痛26例，缺血性脑卒中18例，贫血15例，其他8例，按前瞻、随机原则分为治疗组和对照组，治疗组176例，男90例，女86例，最小年龄16岁，最大83岁，平均54.2岁；对照组175例，男17例，女78例，最小年龄17岁，最大80岁，平均53.6岁。两组在性别、年龄、病程及病种（临床诊断）无明显差异，有可比性。 1.2. 治疗方法 两组病人有合并其他病症者予