妊娠期糖尿病孕期干预对妊娠结局的影响.pdfVIP

浙江临床医学2014年9月第16卷第9期 ·1361· 妊娠期糖尿病孕期干预对妊娠结局的影响 邱丽萍 【摘要】 目的 探讨妊娠期糖尿病 的孕期干预对妊娠结局 的影响。方法 回顾性分析妊娠糖尿病 （GDM ）患者 120例 ，将 孕期通过干预后血糖控制 良好 的76例孕妇为干预实验组 ，将未予孕期干预 、血糖控制不佳者44例为干预对照组 ，同时 ，随机 抽取 110例血糖正常的分娩孕妇为正常对照组 ，比较三组孕妇妊娠结局及 围生儿结局 。结果 干预实验组早产 、羊水过多、巨 大儿 、FGR 、糖尿病酮症 、新生儿低血糖 、新生儿窒息及高胆红素血症 的发生率及剖宫产率均低于干预对照组 ，差异有统计 P P 学意义 （ 0.05 ），而其与正常对照组 比较差异无统计学意义 （ 0.05 ）。结论 妊娠期糖尿病孕期有效干预可明显降低母婴 并发症 的发生率 ，改善母婴结局 ，甚至达到正常孕妇水平 。 【关键词】 妊娠期糖尿病 孕期干预 妊娠结局 剖宫产率 【Abstract 】 Objective To study the influence of pregnancy intervention on the pregnancy outcomes of gestational diabetes mellitus. Methods One hundred and twenty cases of GDM were analyzed ，which were divided into the intervention group which have intervention during pregnancy and blood glucose well-controlled （76 patients ）and intervention control group which have no intervention during pregnancy and blood glucose poor-controlled （44patients ），and 110 healthy pregnant women were in the control group ..Pregnancy outcomes and complications were compared. Results The incidence of premature delivery. polyhydrnios.great children.fetal growth restriction （FGR ）. diabetes ketoacidosis .neonatal hypoglycemia .neonatal asphyxia .hyperbiliruoinemia and cesarean section in intervention group were significantly lower than that in intervention cont P rol group （ 0.05 ）.Conclusion The incidence of complications among maternal and child is significantly decreased and even close to the level of normal pregnant women by effectively prenatal intervention of GDM. 【Key words 】 Gestational diabetes mellitus Pregnancy intervention Pregnancy outcome Ces