茵栀黄口服液配合熊去氧胆酸治疗妊娠期肝内胆汁淤积症120例的临床分析.docVIP

精品论文 参考文献 茵栀黄口服液配合熊去氧胆酸治疗妊娠期肝内胆汁淤积症120例的临床分析 张邑江 　　（四川省成都市大邑县人民医院 四川 大邑 611330） 　　【摘 要】目的：探讨茵栀黄口服液配合熊去氧胆酸治疗妊娠期肝内胆汁淤积症的临床疗效。方法：按照治疗方案不同将我院收治的120例ICP患者分为实验组64例和对照组56例，实验组患者给予茵栀黄口服液联合熊去氧胆酸治疗，对照组患者给予熊去氧胆酸治疗，比较两组患者临床疗效及治疗前后ALT、TBA、CG水平变化情况。结果：实验组患者临床疗效显著优于对照组，差异具有统计学意义（P＜0.05）；实验组患者治疗后ALT、TBA、CG水平均显著低于对照组，差异具有统计学意义（P＜0.05）。结论：茵栀黄口服液配合熊去氧胆酸治疗妊娠期肝内胆汁淤积症疗效显著，能够有效改善患者ALT、TBA、CG水平，减轻黄疸及皮肤瘙痒症状，得到延长孕周，改善妊娠结局的目的，临床应用价值较高。 　　【关键词】茵栀黄口服液；熊去氧胆酸；妊娠期肝内胆汁淤积症 　　【中图分类号】R714.2 【文献标识码】B 【文章编号】1004-6194（2015）01-0132-02 　　Analysis of the patients with intrahepatic cholestasis of pregnancy by Wormwood Zhi yellow oral liquid combine with ursodesoxycholic acid 　　Zhang Yijiang The peoplersquo;s hospital of Dayi, Sichuan, Chengdu(611330) 　　【Abstract】Objective：To explore the clinical effects of intrahepatic cholestasis of pregnancy by Wormwood Zhi yellow oral liquid combine with ursodesoxycholic acid. Methods：120 cases of patients with intrahepatic cholestasis of pregnancy were divided into experiment group(64 cases) and control group(56 cases) according to different methods. The experiment group were treated by Wormwood Zhi yellow oral liquid combine with ursodesoxycholic acid, the control group were treated by ursodesoxycholic acid. The clinical effects, the levels of ALT, TBA, CG were compared for the two groups. Results：The clinical effects of experiment were higher than the control group(P＜0.05); The levels of ALT, TBA, CG for the experiment group were lower than the control group(P＜0.05). Conclusion：It has significant effect for the patients with intrahepatic cholestasis of pregnancy by Wormwood Zhi yellow oral liquid combine with ursodesoxycholic acid, it can improve the levels of ALT, TBA, CG, reduce the symptom of jaundice, pruritus, prolong the gestational age, improve the pregnancy outcome. It has high clinical value. 　　【Keywords】Wormwood Zhi yellow oral liquid; ursodesoxycholic acid; intrahepatic cholestasis of pregnancy 　　引言 　　妊娠期肝内胆汁淤积症（ICP）在孕妇妊娠中晚期较为常见，实验室检查可发现血清胆汁酸和转氨酶水