过敏原与哮喘、荨麻疹、湿疹等相关疾病关系的探讨.docVIP

精品论文 参考文献 过敏原与哮喘、荨麻疹、湿疹等相关疾病关系的探讨 刘士彬 李韧（安徽省阜阳市第五人民医院 236000） 【中图分类号】R593.1 【文献标识码】A 【文章编号】1672-5085 (2010)33-0057-02 【摘要】 目的 研究人体血清中过敏原检测结果与哮喘\荨麻疹\湿疹之间的关系,为临床预防和治疗提供依据.方法:采用ElISA法对400例过敏患者及正常人血清中总IgE及各种特异性IgE进行检测,其中哮喘患者18例,荨麻疹患者255例,湿疹患者127例.并对检测结果进行统计学分析.结果:哮喘\荨麻疹\湿疹患者的总IgE阳性率普片增高并高于对照组,特异性IgE阳性率高于对照组.其中哮喘患者吸入组特异性IgE增高,荨麻疹\湿疹组食入组特异性IgE增高显著.结论:过敏反应与过敏原有着密切的关系,其中本地区哮喘患者多由吸入性花粉\粉尘螨等引起,荨麻疹\湿疹多由食入性如虾蟹瓜果牛奶\鸡蛋等引起,亦有少量是由于接触外源性异物引起,因此过敏原的检测对于临床预防和治疗过敏性疾病有着及其重要的指导作用. 【Abstract】 objective: To study the human serum allergy test results and asthma, eczema, urticaria, the relationship between clinical prophylaxis and treatment, to provide the basis. Method: Using EliSA for 400 cases of patients with normal serum allergy and total IgE and various testing, including specific IgE 18 patients with asthma, eczema, urticaria, patients with 127 255. Result: Asthma, eczema, urticaria, total IgE doppler rate of patients with higher and higher than those in the control group, the piece rate higher than control group. Specific IgE among patients with asthma, inhaled group specificity, eczema, urticaria IgE group eating group significantly increased IgE specificity. Conclusion: Allergic reactions is closely related with the allergens, including the area more than patients with asthma by dust mites inhaled pollen \ \ eczema, urticaria caused by eating more fruit milk as shrimp crab etc, also caused \ eggs with small is due to exogenous caused by foreign contacts, thus allowing the test for the prevention and treatment of allergic disease clinical is utmostly important guiding role. 过敏是最常见的一种变态反应，涉及面非常广泛，仅支气管哮喘患者在国内就近3千万人，其他如荨麻疹\湿疹也极为常见,给阜阳地区广大患者带来了极大的痛苦. 防治过敏反应性疾病的关键在于发现过敏原并有效避免与之接触。传统皮试方法既痛苦又无法避免，对于高过敏体质患者具有一定生命危险性的问题［1］，因此，过敏原体外检测方法已成为一种必然的趋势。我科室引进了体外检测过敏原,填补了这一领域的空白,对最近几年来我科检测的过敏原进行了总结分析,找出过敏原与几种常见的过敏疾病之间的关系,为阜阳地区过敏性疾病的预防和治疗有着极其重要的临床价值,同时也为广大患者带来了极大的便利. 材料:我科室自06年开展过敏原检测至今总共具有不同临床表现的400例过敏患者血清和40例正常人血清为对照组.其中成年男性有60例,女性120例,其中14岁以下儿童220例,成人多为荨麻疹\湿疹发病,无哮喘发病,儿童荨麻疹湿疹发病20