dna修复蛋白xp f影响肾癌细胞顺铂耐药的作用与机制研究word格式论文.docxVIP

缩略语表英文缩写英文全称中文全称DNADeoxyribonucleic acid脱氧核糖核酸NERNucleotide excision repair核苷酸切除修复XPFXeroderma pigmentosum complementation group FERCC1Excisionrepaircross-complementationgroup 1XPAXeroderma pigmentosum complementation group A着色性干皮病互补群 F 切除修复交叉互补群 1 着色性干皮病互补群 ARNAiRibonucleic acid interference核糖核酸干扰FITCFluorescein isothiocyanate异硫氰酸荧光素PIPropidium iodide碘化丙啶shRN AShort hairpin ribonucleic acid短发夹核糖核酸XPGXeroderma pigmentosum complementation group G着色性干皮病互补群 GHRRHomologous recombination repair同源重组修复G418Geneticin新霉素PBSPhosphate buffered saline磷酸盐缓冲液DAB3,3-Diaminobenzidine3,3-二氨基联苯胺DMSODimethyl sulfoxide二甲基亚砜PMSFPhenylmethyl sulfonylfluoride苯甲基磺酰氟化物SDSSodium dodecyl sulfate十二烷基硫酸钠PAGEPolyacrylamide gelelectrophoresis聚丙烯酰胺凝胶电泳TEMEDN,N,N,N-TetramethylethylenediamineN,N,N,N-四甲基二乙胺GAPDHGlyceraldehyde-3-phosphate dehydrogenase甘油醛-3-磷酸脱氢酶PVDFPolyvinylidene fluoride聚偏二氟乙烯TrisTris (hydroxymethyl) aminomethane三（羟甲基）氨基甲烷BSABovine serum albumin牛血清白蛋白PBSTPhosphate Buffered Saline Tween-20吐温磷酸盐缓冲液EDTAEthylenediaminetetraacetic acid乙二胺四乙酸NP-40Nonyl phenoxypolyethoxylethanol壬基酚聚乙氧基醇RNase ARibonuclease A核糖核酸酶 APLBPassive lysis buffer被动裂解缓冲液LAR IILuciferase assay reagent II荧光素酶检测试剂 IIRLUsRelative light units相对发光强度单位X-Gal5-bromo-4-chloro-3- indolyl-β-D- galactopyr anosideD-半乳糖苷GG-N ERGlobal- genome nucleotide excision repair全基因组核苷酸切除修复Transcription-coupled nucleotide excisionTC-NERrepair转录偶联核苷酸切除修复DNA repair protein XPF affects cisplatin resistance of renal cancer cellsAbstractAccording to the data from the Ministry of Health of the Peoples Republic of China, the incidence of renal cancer is among the top ten of malignant tumors of the male, raising year by year. Among the tumors of the urogenital system, the incidence of renal cancer ranks second only to bladder cancer. The early stage or intermediate stage renal cancer is treated the same as other cancers, mainly by surgical operation. However, since renal cancer is resistant to traditional chemotherapeutic drugs such as cisplatin, the