力学载荷促进软骨传质的仿真分析-simulation analysis of mechanical load promoting mass transfer of cartilage.docxVIP

AbstractArticular cartilage has a milky white and light blue color, and a smooth and translucent surface. It possesses multiple irreplaceable special features and plays an important role. But articular cartilage is the predilection site of clinical disease and it is of poor repair ability. Articular cartilage defect often causes joint dysfunction and other diseases, which affects the normal activities and daily life of human. Thus the study of articular cartilage has received wide attention at home and abroad. The normal transfer process of articular cartilage needs some external loads. In this paper, the Finite Element Method is used to simulate and analyze the articular cartilage transfer under the external loads . According to the simulation results, the regularity of mass transfer under different loads is studied, which provides a scientific basis for clinical treatment and tissue repair.According to the Ficks second law, the law of conservation of mass and the mathematical identity between heat and mass diffusion in the theory of mass transfer, the simulation method of mass transfer was proposed. By using the finite element software- ANSYS to establish cartilage model, applying the static compression to load model , and comparing the simulation results with the experimental results, it is found that they have a good correlation. Thus the correctness of the simulation method is proved.By studying mass transfer under the dynamic compression and mass transfer under the different dynamic compression parameters on the basis of simulation model in the static compression, the results show that:(1) When applying load on the articular cartilage, the velocity of mass transfer becomes quicker. (2) Under dynamic compression loading, the mass transfer is very slow in the deep and the middle layer during the initial period, while it is very fast in the superficial layer. But with the increase of time, the concentration grows slowly in the superficial layer and tends to a sta