炎毒清合剂制备及临床应用.docVIP

炎毒清合剂制备及临床应用 　　[摘要] 目的 总结炎毒清合剂的制备工艺，探讨其临床疗效。 方法 选择本院2009年10月～2010年12月收治的慢性鼻窦炎患者40例，咽喉炎50例，根据年龄给予不同剂量治疗，口服7～10 d为1个疗程，评价治疗效果。炎毒清合剂的制备采用水煎煮法提取，鉴别按照《中国药典》附录中的照薄层色谱法，以黄芩甙为对照。 结果 慢性鼻窦炎患者治疗后，有效29例（72.5%），好转8例（20.0%），无效3例（7.5%），总有效率达92.5%。咽喉炎患者治疗后，有效34例（68.0%），好转11例（22.0%），无效5例（10.0%），总有效率为90.0%。 结论 自制炎毒清合剂治疗慢性鼻窦炎、咽喉炎效果良好，并且该工艺制作简单，合剂质量可靠，有一定推广价值。 　　[关键词] 炎毒清合剂；制备；慢性鼻窦炎；临床疗效 　　[中图分类号] R282 [文献标识码] A [文章编号] 1674-4721（2012）02（a）-0109-02 　　 　　Preparation and clinical application of Yanduqing mixture 　　ZHENG Hongbing GONG Yongjian 　　Cili Peoples Hospital of Zhangjiajie City in Hunan Province, Cili 427200, China 　　[Abstract] Objective To summarize preparation process and its clinical efficacy of Yanduqing mixture. Methods Forty patients with chronic sinusitis and 50 cases with pharyngitis in our hospital from October 2009 to December 2010 were given Yanduqing mixture treatment based on age, 7-10 days for a course, evaluated the treatment effect. Yanduqing mixture was prepared by decoction Brewing extraction, identification according to Chinese Pharmacopoeia Appendix According to TLC, to baicalin as the control. Results After treatment of sinusitis patients, it was effective in 29 cases (72.5%), improved in 8 cases (20.0%), ineffective in 3 cases (7.5%), total effective rate was 92.5%. After treatment of pharyngitis patients, it was effective in 34 cases (68.0%), improved in 11 patients (22.0%), ineffective in 5 cases (10.0%), total effective rate was 90.0%. Conclusion The effect of Yanduqing mixture in treatment of chronic sinusitis, pharyngitis is good, and preparation process is simple, the quality is dependable, and there is a certain spread value. 　　[Key words] Yanduqing mixture; Preparation; Chronic sinusitis; Clinical efficacy 　　 　　炎毒清合剂是本院制剂室配制的纯中药制剂，用于鼻窦炎、咽喉炎、扁桃体炎等症。经过多年的临床使用观察，其疗效确切，且未见明显的毒副作用。本文笔者选择本院采用炎毒清合剂治疗的慢性鼻窦炎、咽喉炎患者资料，以及总结的本院制备工艺及鉴别方法，报道如下： 　　1 资料与方法 　　1.1 一般资料 　　选择本院2009年10月～2010年12月收治的鼻窦炎患者40例，全部患者诊断均符合国家中医药管理局1995年《中医病症诊断与疗效标准》[1]。40例患者中，男28例，女