超声心动图对原发性高血压无左室肥厚患者心功能评估.docVIP

超声心动图对原发性高血压无左室肥厚患者心功能评估 　　［摘 要］ 目的 应用超声心动图对原发性高血压无左室肥厚患者心 功能进行评估。方法 应用常规二维、M型超声心动图测量射血分数(EF)、 左心室短轴缩短率 (FS)；应用组织多普 勒成像（DTI）及脉冲多普勒(PDW)技术分别检测二尖瓣环舒张期运动速度及二尖瓣口血流频 谱，并进行对比研究。结果 1.高血压组与对照组左室心肌质量指数无显 著性差别（P＞0.05）；2.高血压组患者的射血分数(EF)、左心室短轴缩短率 (FS)与 对照组均无显著性差异，（P＞0.05）；3.高血压组患者E/A、E1/A1较对照组显著降低 （P＜0.01），E2/A2有降低的趋向但无显著性差异(P＞0.05)。左室等容舒张时 间（IVRT）显著延长(P＜0.01)，但减速时间（DT）无统计学差异(P＞0 .05)；结论 1.高血压患者在发生左室肥厚前已有舒张功能异常；2.DT I技术比PDW技术准确，二者结合，可以为评估左室舒张功能提供更客观的依据。 　　［关键词］ 高血压；左室；舒张功能；组织多普勒成像 　　中图分类号：R544.1 　　文献标识 码：A 　　文章编号：1009-816X(2007)05-0295-03 　　Assessment of Heart Function in Patients with Essential Hypertension without Left Ventricular Hypertrophy by Echocardiography. ZHAO Jun-fe ng, LIU Sheng-xiang, CAI Jin. Post Tele Hospital of Zhejiang, Zhejiang, 310005,China 　　［Abstract］ Objective To assess heart function in patients with essential hypertension without left ventricular hypertrophy by echocardiography . Methods Ejection fraction (EF), fractional shortening (FS) wer e assessed in control group and hypertensive patients by M-Mode Echocardiography . Mitral inflow velocity in early diastole(E) and late diastole(A), and mitral a nnular velocity E1 A1 were measured by Doppler Tissue Imaging(DTI) and Pulse D oppler Technic (PDW). The results of two groups were compared. Results In hypertensive patients, E/A and E1/A1 were lower(P＜0.01), while t he i sovolumic relaxation time(IVRT) was longer than that in control group(P＜0. 01).But there was no statistic significant difference in left ventricular mass inde x (LVMI), EF and FS between hypertensive group and control group (P＞0.05). 　　The deceleration time (DT) of two groups has no significant difference (P＞0.0 5).Conclusions Patients with hypertension may have abnormality of d iastolic function prior to the development of LVH. DTI is more accurate than con ventional Doppler. The combination of two methods can provide more objective bas is in assessment of left ventricular diastolic function. 　　［Key words］ Hypertension；Left ve