自补偿表面等离子体共振光纤生化传感器-光学工程专业论文.docxVIP

自补偿表面等离子体共振光纤生化传感器Self-reference Surface Plasmon Resonance(SPR)Fiber Biosensor AbstractSurface plasmon resonance(SPR)has become a new technology for label．flee detection and biochemical detection．Due to the miniaturization，portable，cost．effective，remote and real—time detection high sensitivity and fast response，SPR has been extensively investigated for chemical and biological sensing applications．On account of the high sensitivity and stability of the fiber-optic SPR sensor．it has a hi曲requirement forthe external environment while remote biological and environmental detection in an extemal environment．However，the environmental condition fbulk re矗acti ve index，external temperature)will influence the performance of SPR sensor for in situ measurement，thereby reducing the stability and accuracy of the sensor．So self_reference SPRsensor gain widespread attention in recent years．This thesis is focus on self-reference SPR sensing technology，which includes the following major works：Firstly，this paper describes the features，application and history of SPR technologY development，and states the present research situation and future development of the SPR sensor．Then，we theoretically introduce the sensing theory of SPR and design the softwaredevelopment platform of virtual instrument based on the software LabVIEW．Aimin2 at theseveral different SPR biosensors we designed in this paper，we design and build a SPR sensing system．In addition，the primary element and their producing technology are introduced in this paper．Next，several self-reference SPR biosensors with different operating principle and sensing element construction are presented and then the research model of our self-reference fiber—optic SPR sensor is proposed，which can realize bulk refractive index or external temperature compensation．The compensation characteristic and the biochemicaI detectioncapability ofthese SPR biosensors can be demonstrated by experiments．Finally，combining with the above we design a self-refere