宝石ct血管成像在冠心病诊断的应用分析-application analysis of gem ct angiography in diagnosis of coronary heart disease.docxVIP
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宝石ct血管成像在冠心病诊断的应用分析-application analysis of gem ct angiography in diagnosis of coronary heart disease
汕头大学医学院硕士学位论文
汕头大学医学院硕士学位论文
II
II
GCTA对冠状动脉狭窄诊断有较高的准确性,可作为高危人群普查筛选的首选方法之
一。
关键词 宝石 CT 血管成像;冠状动脉造影;冠心病
III
III
Abstract
Objective
The objective of the current study was to evaluate the accuracy and feasibility of Gemstone Computed Tomography Angiography(GCTA) in detecting coronary artery stenosis in patients probability for having CAD when compared with invasive angiography. To explore the diagnosis of CAD and its clinical signification with gemstone computed tomography (GCT).
Subjects and Methods
36 patients with known or suspected CAD in the First Affiliated Hospital of Shantou University Medical College during Mar. 2010 to Apr.2011 were studied. Each patient underwent CTA and conventional catheter-based selective coronary angiography (CAG) which served as gold standard in 1 week. For the analysis of GCTA and CAG, the coronary artery tree was broken down in 15 segments after a modified American Heart Association (AHA) classification and all segments were analysed individually. A luminal narrowing of ≥50% based on visual estimation was considered significant in both modalities. The diagnostic accuracy of GCTA was expressed as sensitivity, specificity, positive predictive value, negative predictive value and diagnose accordance rate.
Results
Of a total of 540 coronary artery segments, 523(97%) were visible by GCTA and CAG simultaneously. The GCTA had a sensitivity of 90.7%, specificity of 98.7%, positive predictive value of 90.0%, negative predictive value of 98.9%, diagnose
PAGE
PAGE IV
accordance rate of 98.0%, respectively.
Conclusion
The GCTA has a high accuracy for the detection of significant coronary stenosis and therefore can be considered as a valuable noninvasive technique.
Key Words
Gemstone computed tomography angiography ; Coronary angiography ; Coronary atherosclerotic heart disease
英文缩写
缩略词
英文全名
中文名
AM
acute marginal branch
锐缘支
CACS
coronary artery calcification score
冠状动脉钙化积分
CAD
coronary atherosclerotic heart disease
冠状动脉粥样硬化性心脏病
CAG
coronary angi
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