纳米受限下丝素蛋白的分子取向和力学性能分析-molecular orientation and mechanical properties of silk fibroin under nano - confinement.docxVIP
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纳米受限下丝素蛋白的分子取向和力学性能分析-molecular orientation and mechanical properties of silk fibroin under nano - confinement
纳米受限下丝素蛋白的分子取向和力学性能研究英文摘要ThemolecularorientationanditscorrelationwithmechanicalpropertiesofsilkproteinconfinedatnanoscaleAbstractAlargenumberofthenanomaterialsarepreparedwiththehigh-speeddevelopmentofnanotechnologyinrecentyears.Thepropertiesofnanomaterialshaveanunprecedentedchangescomparedwiththeothermaterials,suchasmechanical,electrical,thermalandopticalproperties.Superiorityofnanomaterialsmadeithadbeenwidelyusedinnanotechnologyfield.Theresearchofthemolecularorientationandmechanicspropertiesofsilkfibroinwithnanoconfinementplayedanimportantguidingroletopreparethemicrophotoelectricdevices,biologicalsensorsanddetectors.Althoughthemechanicspropertiesofelectrospunsilkfibers,nativesilkfiberandregeneratedsilkfibroinfilmhadbeenstudiedforrecentdecades,therelationshipbetweenthemolecularorientationandmechanicspropertiesofsilkfibroinhadbeennotstudied.Ourstudieswerefocusoncontrollingthesilkfibroinmolecularorientationundernanoconfinementanditsmechanicsproperties.Thespecificdetailedstudiesweresummarizedasfollowings:Theregeneratedsilkfibrionsolutionwassuccessfullyextractedfromsilkcocoon.Thehigh-qualitysilkfibroinnanowireswithdifferentdiameterswerepreparedbyvacuum-basedwettingmethod.Scanningelectronmicroscope(SEM)andAtomicforcemicroscope(AFM)wereusedtocharacterizethemorphologyofthenanowires.ThemolecularchainsorientationofsilkfibroinwascharacterizedbythegrazingincidentX-raydiffraction(GIXRD).Ourresultssuggestedthattheorientationofsilkfibroinmolecularwasincreasedwiththedecreasingdiameterofnanowires.Theelasticmodulussequencesoftheregeneratedsilkfibroinfilmsandthenanowireswhichweretreatedwithorganicsolventssuchasmethanol,ethanolorthroughsteam-autoclavingfromhightolowisEwatertreatedEmethanoltreatedEethanolEuntreated.Thisresultsthattheincreasinginβ-sheetcontentcouldresultinginahighertheelasticmoduluswasexpectedaspreviouslydemonstrated.英文摘要纳米受限下丝素蛋白的分子取向和力学性能研究TheAFMnanoindentationtechniqueprovidesafeasibleandeffectivetooltoevaluatethemechanicalpropertiesofindividualnanowire.Wehavefoundth
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