USED IN MIGRAINE用于偏头痛的药物ppt课件.ppt

DRUGS USED IN MIGRAINE;Migraine is a neurological syndrome that can cause a wide range of symptoms during an attack. The most commonly thought of symptom is headache. It is widespread in the population. In the U.S., 18% of women and 6% of men report having had at least one migraine episode in the previous year, with seriousness ranging from an annoyance to a life-threatening and/or daily experience. ;Overview;The word migraine is French in origin and comes from the Greek hemicrania, as does the Old English term megrim. Literally, hemicrania means half (the) head. ;Migraines secondary characteristics are inconsistent. Triggers precipitating a particular episode of migraine vary widely. The efficacy of the simplest treatment, applying warmth or coolness to the affected area of the head, varies between persons, sometimes worsening the migraine. A particular migraine rescue drug may sometimes work and sometimes not work in the same patient. Some migraine types dont have pain or may manifest symptoms in parts of the body other than the head. ;;Classification;;Migraine without aura;In order to diagnose migraine without aura, there must have been at least five attacks not attributable to another cause that fulfill the following criteria: 1. Headache attacks lasting 4–72 hours when untreated 2. At least two of the following characteristics: Unilateral location Pulsating quality Moderate or severe pain intensity Aggravation by or causing avoidance of routine physical activity 3. During the headache there must be at least one of the following associated symptom clusters: Nausea and/or vomiting Photophobia and phonophobia Where these criteria are not fully met, the problem may be classified as probable migraine without aura but other diagnoses such as episodic tension type headache must also be excluded.;Migraine with aura;In order to diagnose migraine with aura, there must have been at least two attacks not attributable to another cause that fulfill the following criteria: