髓鞘碱性蛋白、tnf-a和il-6在实验性大鼠急性重症胰腺炎脑损伤中的水平变化及相关性的研究-changes of myelin basic protein, tnf - a and il - 6 levels and their correlations in experimental rats with acute severe pancreatitis.docxVIP

下载本文档

6
0
约4.78万字
约 41页
2018-08-07 发布于上海
举报
版权申诉

髓鞘碱性蛋白、tnf-a和il-6在实验性大鼠急性重症胰腺炎脑损伤中的水平变化及相关性的研究-changes of myelin basic protein, tnf - a and il - 6 levels and their correlations in experimental rats with acute severe pancreatitis.docx

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

髓鞘碱性蛋白、tnf-a和il-6在实验性大鼠急性重症胰腺炎脑损伤中的水平变化及相关性的研究-changes of myelin basic protein, tnf - a and il - 6 levels and their correlations in experimental rats with acute severe pancreatitis

万方数据万方数据目录中文摘要······························································································· （1）英文摘要······························································································· （2）论文题目······························································································· （3）前言····································································································· （3）材料与方法······················································································（4）结果······························································································· （7）讨论····························································································· （16）结论····························································································· （19）参考文献······················································································· （20）文献综述····························································································· （23）参考文献·························································································（33）英文缩略语表······················································································· （37）攻读学位期间发表文章情况····································································· （38）个人简历····························································································· （39）致谢··································································································· （40） 1内蒙古医科大学硕士研究生学位论文（ 1 内蒙古医科大学硕士研究生学位论文（2015）中文摘要目的:探讨髓鞘碱性蛋白(myelin basic protein MBP)、肿瘤坏死因子-α（TNF-α）和白细胞介素-6（IL-6）在实验性急性重症胰腺炎脑损伤大鼠模型血清和脑脊液中的水平变化,分析各因子与急性重症胰腺炎脑损伤发展几个随机时间点病情的相关性，为临床急性重症胰腺炎脑损伤的诊断及治疗提供实验依据.方法:选取 40 只 SD 大鼠随机分为假手术组(sham operation SO 组 n=10)和急性重症胰腺炎脑损伤组(SAP 组,n=30).SO 组经十二指肠乳头逆行胰胆管穿刺注射生理盐水,PE 经十二指肠乳头逆行胰胆管穿刺注射 5% 牛磺胆酸钠(sodium taurocholate)诱导建立大鼠急性重症胰腺炎脑损伤模型。SO 组大鼠于手术后 1d 全部处死，SAP 组分别于造模后 1、3、7day 各处死 10 只，各取 SO 组和 SAP 组大鼠的脑组织和胰腺组织，观察脑微血管内白细胞聚集及附壁现