CPAP呼吸机氨溴索治疗新生儿呼吸窘迫综合征疗效分析.docVIP

CPAP呼吸机氨溴索治疗新生儿呼吸窘迫综合征疗效分析 　　[摘要] 目的 探讨CPAP呼吸机、氨溴索治疗新生儿呼吸窘迫综合征（NRDS）的临床疗效。 方法 方便选取2013年8月―2016年7月于该院儿科住院部确诊NRDS的86例患儿纳入研究并随机分组，对照组42例患儿采用CPAP呼吸机治疗，观察组44例患儿则联合氨溴索静滴治疗，观察两组患儿临床疗效差异。 结果 经治疗，两组患儿氧分压（PaOP）较治疗前明显升高，吸氧浓度（FiO2）、二氧化碳分压（PaCO2）则降低，差异有统计学意义（P0.05）；观察组患儿住院时间、氧疗时间均更短（P0.05）；对照组总有效率73.81%，观察组为93.19%，组间比较差异有统计学意义（P0.05）；观察组并发症发生率6.82%，低于对照组的23.81%，差异有统计学意义（P0.05）。 结论 CPAP呼吸机、氨溴索治??RDS疗效显著，可提高临床疗效，更好地改善血气指标，且安全可靠，值得推广。 　　[关键词] CPAP呼吸机；氨溴索；新生儿呼吸窘迫综合征；血气指标 　　[中图分类号] R722.1 [文献标识码] A [文章编号] 1674-0742（2017）01（c）-0072-03 　　Analysis of Curative Effect of CPAP Ventilator and Ambroxol in Treatment of Neonatal Respiratory Distress Syndrome 　　LI Yan， XU Shu-qin， WANG Xiao-zhi 　　Department of Pediatrics， Fangshan Districct First Hospital， Beijing， 102400 China 　　[Abstract] Objective To discuss the clinical curative effect of CPAP ventilator and ambroxol in treatment of neonatal respiratory distress syndrome. Methods Convenient selection 86 cases of children with NRDS in the inpatient department in our hospital from August 2013 to July 2016 were selected and randomly divided into two groups， the control group （42 cases） were treated with CPAP ventilator， while the observation group （44 cases） were treated with intravenous drip of ambroxol， and the difference in the clinical curative effect of the two groups was observed. Results After treatment， the PaO2 of the two groups was obviously increased compared with that before treatment， FiO2 and PaCO2 decreased and the differences had statistical significance（P0.05）， and the length of stay and time of therapy using oxygen in the observation group were shorter（P0.05）， and the difference in the total effective rate between the control group and the observation group had statistical significance，（73.81% vs 93.19%）（P0.05）， and the incidence rate of complications in the observation group was lower than that in the control group， （6.82% vs 23.81%）， and the difference had statistical significance（P0.05）. Conclusion The curative eff