TCD监测脑出血患者颅内压临床研究.docVIP

TCD监测脑出血患者颅内压临床研究 　　【摘要】 目的：探讨经颅多普勒超声（TCD）监测脑出血患者的颅内压的临床意义。方法：选取2014年8-10月由本院神经内科收治的64例脑出血患者为研究对象，将脑出血患者作为观察组，并将同时期门诊健康者作为对照组，分别对两组患者行经颅多普勒超声检测颅内压，比较两组患者的颅内压以及各项脑血流动力学参数。结果：对观察组患者共进行了104次TCD和腰穿测压检测，对照组患者共进行了40次检测，频谱结果提示，随着颅内压的升高，平均血流速度与舒张期血流速度逐渐减小，与颅内压成反比例关系，但收缩期血流速度的变化规律不明显，组间比较差异无统计学意义（P0.05）；而搏动指数和阻力指数随着颅内压的增大逐渐增大，各组间比较差异均具有统计学意义（P0.05）。结论：经颅多普勒超声检测脑出血患者的颅内压，具有无创伤、检测结果安全、可靠等优势，对患者的病情具有一定的指导作用。 　　【关键词】 经颅多普勒； 脑出血； 颅内压 　　Clinical Research on TCD Monitoring Intracranial Pressure in Patients with Intracerebral Hemorrhage/TAN Xi-xi，LIN Tao，ZHANG Li-jun，et al.//Medical Innovation of China，2015，12（08）：050-052 　　【Abstract】 Objective：To evaluate clinical significance of transcranial Doppler ultrasonography monitoring intracranial pressure in patients with cerebral hemorrhage.Method：Sixty four patients with cerebral hemorrhage admitted by the department of neurology of Hospital from August 2014 to October 2015 were selected as research subjects， patients with cerebral hemorrhage were divided into the observation group， and 64 patients with cerebral hemorrhage admitted simultaneously were divided into the control group，respectively on two groups of patients via transcranial doppler ultrasound detecting intracranial pressure， patients in two groups were subject to tests of intracranial pressure of Doppler ultrasonography and cerebral hemodynamic parameters.Result：Patients in the experimental group patients were subject to 104 times of TCD and lumbar puncture pressure detections，and patients in the control group were subject to 40 times of detections，spectrum results suggest that average blood flow velocity and diastolic blood flow velocity decrease with the increase in intracranial pressure，and they formed inversely proportional relationship with intracranial pressure， the change rule of systolic blood flow velocity was not obvious，and the inter-group difference was no statistically significant（P0.05）.The pulsation index and resistance index increase gradually with the